Considering glucose infusion effects during surgery, in current double-blinded randomized clinical trial, we aimed to evaluate effect of glucose addition to ringer solution on maternal hemodynamic status subsequent to epidural analgesia cesarean section. Ninety women aged between 18 to 40 years old with term singleton pregnancy candidate for elective cesarean section with epidural analgesia will be enrolled and women suffering systemic diseases, mental disorders and body mass index more than 30 kilograms per meter square will be excluded. Prior to surgery, equally, patients will be divided to control and study groups, by randomization.
Study group (45 cases) will receive 1% glucose solution in ringer serum, and control group (45 cases) will receive distilled water added to ringer serum. During administration of epidural analgesia, 8 ml/kg body weight bullous intravenous fluid will be infused during 15 minutes and subsequently, infusion will be continued till end of the operation in dose of 15-20 ml/kg/ min. Study group solution (1% glucose) will be prepared by adding 10 gram of glucose (20 ml) to 1-liter ringer serum and control group solution will be prepared by adding same amount of distilled water to ringer serum, as well. Study parameters including basal hemodynamic variables (blood pressure, heart rate) and prevalence of hypotension side effects including nausea, vomiting and respiratory suppression will be recorded. Overall vasopressors dosage and preoperative and postoperative maternal blood glucose level will be measured.