Comparison of serratus anterior plate block with ropivacaine and ropivacaine-dexmedetomidine combination to reduce pain in patients after thoracotomy surgery

Determining the effective drug and reducing the use of narcotic drugs

Two arm parallel group randomized trial with blinded postoperative care and outcome assessment

Patients undergoing thoracotomy surgery in Imam Khomeini Hospital, Ahvaz Age 18 to 60 years; Class I or II physical condition Patients are randomly assigned to one of the two groups of ropivacaine (R) or ropivacaine-dexmedetomidine (RD). The grouping of patients is random and the patient and the person in charge of registering the patient's information are not aware of the patient's allocation group. Information is entered into the checklist, which includes name, age, gender, height and weight, BMI, pain score, duration of operation, length of stay in ICU, time of walking in ICU and amount of narcotics a

The criteria for entering the study are: Age 18 to 60 years; Class I or II physical status according to the criteria of the Association of Anesthesiologists (ASA); body mass index (BMI) less than 40; No history of drug or alcohol abuse; absence of pregnancy or breastfeeding; No history of coagulation problems or use of anticoagulants; jump fraction higher than 30%; No history of conduction heart block; absence of acute or chronic hepatitis; lack of history of psychiatric diseases; No need for complementary renal treatments or a history of kidney failure; Absence of neuropathy: Exclusion criteria: sensitivity to study drugs and unwillingness of patients to cooperate.

ropivacaine (R)-ropivacaine-dexmedetomidine(RD)

vagus nerve stimulation (VNS)

Allocation of patients is done in random order in this way, which is done using the randomization table. The information is entered into the checklist. The checklists are already numbered by the statistical consultant, and this numbering is the basis for the allocation of patients, but the allocation of numbers to groups will not be revealed until the results are analyzed

In this way, the patient and the specialist doctor are not aware of the type of medicine.Allocation of patients is done in random order in this way, which is done using the randomization table.The patient and the person responsible for registering the patient's information are unaware of the patient's diagnostic group.The information is entered into the checklist. Checklists are already numbered by a statistical consultant and this numbering is the basis of patient allocation, but the allocation of numbers to groups will not be revealed until the results are analyzed. The person responsible for injecting the drug is aware of the injected drug, but in the collection process And data analysis does not participate.