Investigating the effect of vitamin A ophthalmic ointment on reducing pain and accelerating the recovery of corneal abrasions after photorefractive keratectomy

Investigating the effect of vitamin A ophthalmic ointment on reducing pain and accelerating the recovery of corneal abrasions after photorefractiokeratectomy surgery.

Clinical trial with random permutation block method, phase 3 on 28 patients, which are analyzed and used for randomization using SPSS version 22.

Patients will undergo photorefractiokeratectomy with knowledge and consent in the company's study using an excimer device, and they are also free to withdraw from the study at any stage. Their sex, medical history is collected.

Entry criteria: American Society of Anesthesiology class I and II People with refractive error myopia and regular astigmatism (both together or each one alone) The amount of optical zone 5.6 - 5.7, people with spherical equivalent maximum of 3.5 diopters. Exclusion criteria: lack of consent to participate in the study, use of contact lenses in the last two months, presence of corneal scratches before surgery, drug use Corneal dystrophies, the presence of any structural disorders of the eye, the presence of pathologies and eye diseases, the presence of systemic diseases (diabetes, vascular collagen disorder, etc.), people with hyperopia, amblyopia

These patients randomly received routine drugs such as chloramphenicol, betamethasone and artificial tears in one eye (control group) and in the other eye as an intervention group, in addition to routine drugs, received sterile vitamin A eye ointment from Iran Nazo brand every 8 hours. It will be a month.

Visual Analog Scale (VAS)

Allocation of patients randomly (using permutation blocks) into two intervention and witness groups (14 people) in such a way that patients will participate in the study with knowledge and consent, based on this, the number of patients who will undergo surgery There are 28 people. PRK was performed by a surgeon and will be included in the study. Then, in these patients, in one eye, routine betas from the family of chloramphenicol, betamethasone and artificial tears (control group) and in the other eye as an intervention group, in addition to routine drugs, received Vitamin A Sterile Eye Ointment from Iran Nazo brand requires every 8 hours to a month and can explain to the drugs that it is possible to take the drug as a drug, then from surgery for patients who want to be able to relieve their pain afterwards. Do. (6 and 24 hours after the operation, 12 and 24 hours after the operation and then daily up to a week) and the time period when the pain starts after the operation and requires the use of painkillers after that and the number of painkillers It consumes extra. Register themselves in the checklist that will be delivered to them on the day of the operation