The changes of interleukin-17, interferon-γ and hs-CRP concentrations of athletes following a single session of exercise in cold and natural conditions.
Introduction: Exercise and stressor environments could lead to some immune changes in human body. The aim of this study was to explore the changes of interleukin 17, interferon-γ and hs-CRP concentrations of athletes after a single session of exercise in cold and natural conditions.
Materials and methods: This study was a randomized clinical trial of a single blind.Ten young male athletes ran on a treadmill for 1h at %60 VO2max in conditions of natural and cold. The interleukin 17, interferon-γ, hs-CRP and cortisol concentrations measured before, immediately after exercise and two hours after (during recovery) and body temperature, pressure scale and athletes’ consummated water during exercise. In order to analyze the data, Repeated Measure and Bonferroni tests and Paired T tests were utilized at the significant level of p<0.05.
Inclusion criteria included; having a history of at least 3 years of continuous and 8 hours per week of exercise endurance; maximal oxygen consumption 50 ml kg min; the absence of any disease of the immune system; vascular Kvrnr and infection in the past month; such as influenza; to colds; respiratory infections Hungarian; or symptoms such as fever; sore throat; runny nose; cough and other infectious diseases. The use of doping substances such as vitamins; dietary supplements; herbs or medications that affect the immune system are effective; Smoking and alcohol 48 hours before the test; Participate in heavy exercise; exposure to adverse environmental conditions; temperature; disease and viral infection during the plan period; were exclusion criteria.
General information
Acronym
Not have
IRCT registration information
IRCT registration number:IRCT201111297255N3
Registration date:2011-12-07, 1390/09/16
Registration timing:retrospective
Last update:
Update count:0
Registration date
2011-12-07, 1390/09/16
Registrant information
Name
Sadegh Satarifard
Name of organization / entity
Tehran University
Country
Iran (Islamic Republic of)
Phone
+98 21 8863 3866
Email address
satarifard@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2011-05-10, 1390/02/20
Expected recruitment end date
2011-06-19, 1390/03/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The changes of interleukin-17, interferon-γ and hs-CRP concentrations of athletes following a single session of exercise in cold and natural conditions.
Public title
Exercise and immune change
Purpose
Basic scienece
Inclusion/Exclusion criteria
Inclusion criteria included; having a history of at least 3 years of continuous and 8 hours per week of exercise endurance; maximal oxygen consumption 50 ml kg min; the absence of any disease of the immune system; vascular Kvrnr and infection in the past month; such as influenza; to colds; respiratory infections Hungarian; or symptoms such as fever; sore throat; runny nose; cough and other infectious diseases. The use of doping substances such as vitamins; dietary supplements; herbs or medications that affect the immune system are effective; Smoking and alcohol 48 hours before the test; Participate in heavy exercise; exposure to adverse environmental conditions; temperature; disease and viral infection during the plan period; were exclusion criteria.
Age
From 20 years old to 30 years old
Gender
Male
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
10
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Tehran University,Department of Physical Education
Street address
Department of Physical Education of Tehran University, Kargrshmaly Street,Tehran
City
Tehran
Postal code
13117-14398
Approval date
2011-05-04, 1390/02/14
Ethics committee reference number
28
Health conditions studied
1
Description of health condition studied
Not Patient- Healthy subjects, young athletes
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
interleukin-17 Concentration
Timepoint
Before, immediately after and 2 h after exercise
Method of measurement
Using ELISA Kit
2
Description
CRP concentration
Timepoint
Before, immediately after and 2 h after exercise
Method of measurement
Using ELISA Kit
3
Description
IFN-γ
Timepoint
Before, immediately after and 2 h after exercise
Method of measurement
Using ELISA Kit
Secondary outcomes
1
Description
Not have
Timepoint
Not have
Method of measurement
Not have
Intervention groups
1
Description
One hour of exercise (running on a treadmill) with 60% of vo2max, in normal environment(4˚c)
Category
Other
2
Description
One hour of exercise (running on a treadmill) with 60% of vo2max, in normal environment(22˚c)
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Yasuj
Full name of responsible person
Satarifard Sadegh
Street address
Tehran University School of Physical Education, Kargrshmaly Street, Tehran
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Investigator
Full name of responsible person
Satarifard Sadegh
Street address
Tehran University School of Physical Education, Kargrshmaly Street, Tehran
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Investigator
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Tehran University
Full name of responsible person
Satarifard Sadegh
Position
MSc student
Other areas of specialty/work
Street address
Tehran University School of Physical Education, Kargrshmaly Street, Tehran
City
Tehran
Postal code
14398-13117
Phone
+98 21 8863 3866
Fax
Email
satarifard@ut.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Tehran University
Full name of responsible person
Satarifard Sadegh
Position
MSc student
Other areas of specialty/work
Street address
Tehran University School of Physical Education, Kargrshmaly Street, Tehran
City
Tehran
Postal code
14398-13117
Phone
+98 21 8863 3866
Fax
Email
satarifard@ut.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Tehran University
Full name of responsible person
Satarifard Sadegh
Position
MSc student
Other areas of specialty/work
Street address
Tehran University School of Physical Education, Kargrshmaly Street, Tehran
City
Tehran
Postal code
14398-13117
Phone
+98 21 8863 3866
Fax
Email
satarifard@ut.ac.ir
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)