Design: cross-over clinical trial. Participants: obese girls aged 8-15 years that were recruited from a private clinic of a pediatrician. The objective: Evaluation the impact of whole-grain consumption on serum levels of adipocytokines and inflammatory bio markers in obese children. Exclusion criteria: history of chronic diseases such as cardiovascular disease (CVD), medication and supplementation use. Setting and conduct: After a 2 week run-in period, participants will be randomly assigned to whole-grain and recommendation group each for 6 weeks. After the first phase of intervention, a 4-week washout period will be applied. Then the participants will be crossed over to the alternate group for additional 6 weeks. To assess the compliance of the participants, we will assess dietary intakes of subjects by the use of dietary records once in every two weeks. Physical activity levels will also be assessed by a physical activity record once in every two weeks. Anthropometric measurements and biochemical assessments including fasting plasma glucose, triglyceride, total-cholesterol, high density lipoprotein cholesterol (HDL-c)-, and low density lipoprotein cholesterol (LDL-c), high sensitivity C-Reactive Protein (hs-CRP), serum amyloid A (SAA), serum inter-cellular adhesion molecule (sICAM-1), serum vascular cell adhesion molecule (sVCAM-1), leptin levels will be measured at the beginning and end of each phases. Appropriate statistical methods will be applied for data analyses. Interventions: usual dietary recommendation includes healthy food choices. First the individual energy requirements will be calculated. The target macro nutrient composition for all participants will be 53% of energy as carbohydrate, 30% of energy as fat and 17% of energy as protein. Subjects will be asked to obtain 50% of their grain servings from whole grain foods each day.