Protocol summary

Summary
Aim: A comparison between therapeutic efficacy of wet-cupping vs. conventional treatment in patients with chronic non-specific low back pain. Design: A controlled, single center, randomized clinical trial. Studied population: Patients between 16-65 years of age with chronic nonspecific low back pain persisting for at least 4 weeks. Sample size: 150 cases. Intervention: -In intervention group: The treatment itself will be performed by a physician using standard techniques in medical centers. Wet-cupping will be applied in 2 stages: between the two scapulas in the first day and in the sacrum area in 2 weeks; Each wet-cupping treatment procedure will last about 20 min and will be conducted in five steps. -In control group: control group will receive the standard conventional treatment for low back pain. This treatment includes: (1) encouragement for early return to usual activities, excluding heavy manual labor, (2) activity alteration to minimize symptoms, (3) medical therapy: e.g., acetaminophen or NSAIDs, (4) short duration muscular relaxants, (5) bed rest not more than 2 days. Outcomes: Primary outcome includes Disability and quality of life index using ODI (Oswestry disability index), and secondary outcome will be the Pain intensity using VAS (Visual analogue scale).

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201302167274N7
Registration date: 2013-02-18, 1391/11/30
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2013-02-18, 1391/11/30
Registrant information
Name
Mohsen Mardani Kivi
Name of organization / entity
Guilan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 13 1321 1470
Email address
mardani@gums.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Guilan University of Medical Science
Expected recruitment start date
2012-11-05, 1391/08/15
Expected recruitment end date
2013-03-05, 1391/12/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
A comparison between therapeutic efficacy of wet-cupping vs. conventional treatment in patients with chronic non-specific low back pain.
Public title
Chronic non-specific low back Pain: comparing the efficacy of wet-cupping and conventional treatment.
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: age 16-65 years; Low back pain persisting for 4 weeks or more. Exclusion criteria: possible spinal pathology (e.g., carcinoma); severe or progressive motor weakness or central disc prolapse in the last 3 years; bleeding disorders (coagulopathies such as hemophilia) and history of treatment with wet-cupping in the last 6 months; radicular or referral back pain with probable discopathy disorders; VAS score lower than 4; and localized tenderness on the spinal process.
Age
From 16 years old to 65 years old
Gender
Both
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size: 150
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee, Guilan University of Medical Sciences
Street address
Vice chancellor for research, Guilan University of Medical Sciences, Namjou avenue
City
Rasht
Postal code
Approval date
2012-10-23, 1391/08/02
Ethics committee reference number
1910231215

Health conditions studied

1

Description of health condition studied
Low back pain
ICD-10 code
M54.5
ICD-10 code description
Low back pain, Loin pain, Low back strain

Primary outcomes

1

Description
Disability index
Timepoint
Baseline assessment, post treatment and final follow-up visit.
Method of measurement
Oswestry Disability Index

Secondary outcomes

1

Description
Pain intensity
Timepoint
Baseline assessment, post treatment and final follow-up visit.
Method of measurement
Visual analogue scale

Intervention groups

1

Description
In intervention group: The treatment itself will be performed by a physician using standard techniques in a medical center. Wet-cupping will be applied in 2 stages: between the two scapulas in the first day and in the sacrum area in 2 weeks; each wet-cupping treatment procedure will last about 20 min and will be conducted in five steps.
Category
Treatment - Devices

2

Description
In control group: control group will receive the standard conventional treatment for low back pain. This treatment includes: (1) encouragement for early return to usual activities, excluding heavy manual labor, (2) activity alteration to minimize symptoms, (3) medical therapy: e.g., acetaminophen, or NSAIDs, (4) short duration muscular relaxants, (5) bed rest not more than 2 days.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam-Reza Clinic of Poursina Hospital
Full name of responsible person
Dr Mohsen Mardani Kivi
Street address
Imam-Reza clinic, Poursina hospital, Parastar avenue
City
Rasht

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research, Guilan University of Medical Sciences
Full name of responsible person
Dr. Abdolrasoul Sobhani, Research chancellor of Guilan university of medical science
Street address
Vice chancellor for research, Guilan University of Medical Sciences, Namjou avenue
City
Rasht
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Guilan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Guilan University of Medical Science
Full name of responsible person
Dr. Mohsen Mardani Kivi
Position
Assistant Professor
Other areas of specialty/work
Street address
Orthopedic Department, Poursina Hospital, Parastar avenue.
City
Rasht
Postal code
Phone
+98 13 1321 1470
Fax
Email
mardani@gums.ac.ir
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Guilan University of Medical Sciences
Full name of responsible person
Dr. Mohsen Mardani Kivi
Position
Assistant Professor
Other areas of specialty/work
Street address
Orthopedic Department, Poursina Hospital, Parastar avenue
City
Rasht
Postal code
Phone
+98 13 1321 1470
Fax
Email
mardani@gums.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Guilan University of Medical Sciences
Full name of responsible person
Dr. Mohsen Mardani Kivi
Position
Orthopedic Surgeon, Assistant Professor
Other areas of specialty/work
Street address
Orthopedic Department, Poursina Hospital, Parastar avenue
City
Rasht
Postal code
Phone
00
Fax
Email
mardani@gums.ac.ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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