Protocol summary

Summary
This study is a double blind clinical trial (patient and assessor). The population includes 45 traumatic comatose patients with GCS≤8 with the age range of 15-75, admitted to ICU, training centers of mazandaran university of medical sciences. The sampling method allocated into three groups, one, two and the control. The test takes place among the patients with a tape recording of the voice, group one(stimulation with familial voice) and two (auditory stimulation by researcher introduced as a nurse), two times per day for 5-15 minutes. The control group, but the usual sounds of the environment, stimulation did not receive a hearing. Means of mMeasurement of consciousness of patients are the Glasgow Coma Scale( GCS) which controlled before, during and 2 minutes after the test takes place. These tests are meanwhile also take place for the control group. The time GCS, vtal signs of patients were well controlled.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201109247537N1
Registration date: 2012-06-07, 1391/03/18
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2012-06-07, 1391/03/18
Registrant information
Name
Fereshteh Araghian Mojarad
Name of organization / entity
Mazandaran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 15 1226 7342
Email address
f.araghian@mazums.ac.ir
Recruitment status
Recruitment complete
Funding source
Mazandaran University of Medical Sciences
Expected recruitment start date
2011-06-10, 1390/03/20
Expected recruitment end date
2011-12-11, 1390/09/20
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of the effect of auditory sensory stimulation with familiar and unfamiliar voices in level of consciousness of traumatic comatose patients admitted to ICU, educational and traputic centers of mazandaran university of medical sciences, 2011.
Public title
Auditory stimulation in level of consciousness of comatose patients
Purpose
Supportive
Inclusion/Exclusion criteria
Inclusion criteria: GCS≤8; traumatic comatose patient; aged between 15 To 75 years. Exclusion criteria: history of brain trauma; history of hearing loss; affection to diabet & cardiovascular disease& fat emboli; opium and drug addiction; otorrhea, Rhinorrhea; skull fracture or bleeding or surgery in temporal region andfFracture or palsy in all organs or eyelid swelling.
Age
From 15 years old to 75 years old
Gender
Both
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size: 45
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Vicen Chancellor of Mazandaran University of Medical Science and Health Services
Street address
Moalem square, Moalem street, Sari, Mazandaran, IRAN
City
Sari
Postal code
4816715793
Approval date
2011-05-18, 1390/02/28
Ethics committee reference number
39-90

Health conditions studied

1

Description of health condition studied
Brain injury
ICD-10 code
S06.9
ICD-10 code description
Intracranial injury, unspecified

Primary outcomes

1

Description
Traumatic comatose patient level of consciousness
Timepoint
Before and between and after intervention 2 times per day till 14 days
Method of measurement
Glascow Coma Scale

Secondary outcomes

empty

Intervention groups

1

Description
First group (stimulation with familial voice)2 times per day for 15 minutes till 14 day were stimulated
Category
Rehabilitation

2

Description
Second group (auditory stimulation by researcher introduced as a nurse) 2 times per day for 15 minutes till 14 day were stimulated.
Category
Rehabilitation

3

Description
The control group, but the usual sounds of the environment, stimulation did not receive a hearing
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Imam Khomaini Hospital Sari
Full name of responsible person
Mohammad Ali Heydari Gorji
Street address
Mazandaran University of Medical Science- Nursing, Nasibeh Nursing and Midwifery School, Sari
City
Sari

2

Recruitment center
Name of recruitment center
Razi Hospital Ghaemshahr
Full name of responsible person
Mohammad Ali Heydari Gorji
Street address
Mazandaran University of Medical Science- Nasibeh Nursing and Midwifery School, Sari
City
Sari

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Research Vice Chancellor of Mazandaran University 0f Medical Science and Health Service
Full name of responsible person
Dr. Ahmad Ali Enayati
Street address
Moalem square; Moalem street
City
Sari
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Research Vice Chancellor of Mazandaran University 0f Medical Science and Health Service
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Mazandaran University of Medical Science and Health Service
Full name of responsible person
Yadollah Jannati
Position
PhD./ Faculty Member
Other areas of specialty/work
Street address
Nasibeh Nursing and Midwifery School, Vesal Street, Amir Mazandarani Bulevard Sari
City
Sari
Postal code
4816715793
Phone
+98 15 1226 8918
Fax
+98 15 1226 8915
Email
jannatiyadolah@gmail.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Mazandaran University of Medical Science and Health Service
Full name of responsible person
Mohammad Ali Heydari Gorji
Position
PhD./ Faculty Member
Other areas of specialty/work
Street address
Nasibeh Nursing and Midwifery School, Vesal Street, Amir Mazandarani Bulevard Sari
City
Sari
Postal code
4816715793
Phone
+98 15 1226 7342
Fax
+98 15 1226 8915
Email
heydarigorji@yahoo.com
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Mazandaran University of Medical Science and Health Service
Full name of responsible person
Fereshteh Araghian Mojarad
Position
MSc Student of Critical Care Nursing
Other areas of specialty/work
Street address
Nasibeh Nursing and Midwifery School, Vesal Street, Amir Mazandarani Boulevard
City
Sari
Postal code
4816715793
Phone
+98 15 1238 5253
Fax
Email
f.araghian@mazums.ac.ir. fereshteharaghian@yahoo.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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