Effect of fast intravenous serum therapy on hospital admisson rate of children with refractory vomitting and gastroenteritis referring to Tabriz Children's Hospital

Our aim in this study is to evaluate the effect of fast intravenous serum therapy on hospital admission rate of children with gastroenteritis. In a randomized and unicentral clinical trial 70 children aged between 2 to 12 from both genders and with moderate gastroenteritis referring to emergency ward of Tabriz Children's Hospital would be involved. Key inclusion criteria would include children aged between 2 to 12 with diarrhea and vomiting which have not responded well to routine oral therapies; not to have electrolite imbalance; not to have severe dehydration; to fulfill an informed consent and exclusion criteria would be to have mild or severe dehydration; to have electorlite imbalance; in shock patients; patients with vomiting or diarrhea alone. Patients will randomly be divided into two control or case group each with 35 subjects. In control group patients will be admitted and visited by a specialist every day and in the case group patients will be treated with intravenous crystalloid solution 30 ml/kg infusion within 2 hours and then visited by a pediatrician to see if they need to be admitted to the internal ward. Primary outcome measures includes skin turgor, level of mucus dryness and desire to drink water; and secondary outcome measure would be occurrence of vomiting after intravenous therapy.

Tabriz University of Medical Sciences