Preventing atrial fibrillation is crucial due to decrease any side effect of admission in the hospital. It has been shown that arrhthmia prevention has an important role in decrease mortality and morbidity of patients who undergo cardiac surgery. In this study, we would like to evaluate and compare the preventive effect of Amiodarone and Lidocaine on post CABG cardiac arrhythmia.
150 patients will be randomly assigned (balanced block randomization) to three groups (A, B, and C). In group A: during the cardiopulmonary bypass and before releasing aortic cross clamp, Lidocaine (4 mg/kg) will be added to the prime. In group B and C: during the cardiopulmonary bypass and before releasing aortic cross clamp, Amiodarone (150 mg) and normal saline (5 cc) will be added to the prime, respectively. DC shock will be applied whenever it is required. Na, K, Ca, Mg, PH, and HCO3 will be evaluated before cross clamping, during CPB time, after release of aortic cross clamp, 1, 6, and 24 hours after entering the ICU. CPK will be evaluated before surgery, 1, 6, and 12 hours after entering the ICU. Outcomes: 1.patients' cardiac rhythm after release of aortic cross clamp, entering the ICU, and entering the ward by holter monitoring.