Protocol summary

Summary
Objectives: To compare the adverse effect of standard percutaneous nephrolithotomy versus & Tubeless percutaneous nephrolithotomy in patients having kidney stone. Design: .a single blind randomized clinical trial. Setting and conduct: The eligible patients having kidney stone who will refer to Shahid Beheshti Hospital during the study period will be enrolled into the trial. Inclusion criteria: Kidney stone; age of 18 to 80 years. Exclusion criteria: Indication of open surgery. Intervention group: Tubeless percutaneous nephrolithotomy. Control group: Standard percutaneous nephrolithotomy. Primary outcome: (a) hemoglobin before and 24 hours after intervention through laboratory testing; (b) hematoma 24 hours after intervention using sonography. Secondary outcome: Pain 24 hours after surgery using VAS. Randomization: The patients will be randomly assigned to intervention and control groups using block randomization. Blinding: The patients will not be aware of the type of intervention. Therefore, the trial will be run as single blind.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201611019014N129
Registration date: 2016-11-18, 1395/08/28
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2016-11-18, 1395/08/28
Registrant information
Name
Jalal Poorolajal
Name of organization / entity
Department of Epidemiology & Biostatistics Hamadan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 81 1838 0090
Email address
poorolajal@umsha.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Expected recruitment start date
2015-04-21, 1394/02/01
Expected recruitment end date
2017-03-19, 1395/12/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of the adverse effect of standard percutaneous nephrolithotomy versus & tubeless percutaneous nephrolithotomy in patients having kidney stone: a single blinded randomized controlled trial
Public title
Comparison of the adverse effect of two methods of nephrolithotomy in patients having kidney stone
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: Kidney stone; age of 18 to 80 years. Exclusion criteria: Indication of open surgery.
Age
No age limit
Gender
Both
Phase
2
Groups that have been masked
No information
Sample size
Target sample size: 58
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Randomization: The patients will be randomly assigned to intervention and control groups using block randomization. Blinding: The patients will not be aware of the type of intervention. Therefore, the trial will be run as single blind.

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Hamadan University of Medical Sciences
Street address
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences, Shahid Fahmideh Ave
City
Hamadan
Postal code
6517838695
Approval date
2015-04-11, 1394/01/22
Ethics committee reference number
IR.UMSHA.REC.1394.37

Health conditions studied

1

Description of health condition studied
kidney stone
ICD-10 code
N20.0
ICD-10 code description
Calculus of kidney

Primary outcomes

1

Description
hemoglobin
Timepoint
before and 24 hours after intervention
Method of measurement
through laboratory testing

2

Description
hematoma
Timepoint
24 hours after intervention
Method of measurement
using sonography

Secondary outcomes

1

Description
Pain
Timepoint
24 hours after surgery
Method of measurement
using VAS

Intervention groups

1

Description
Intervention group: Tubeless percutaneous nephrolithotomy.
Category
Treatment - Surgery

2

Description
Control group: Standard percutaneous nephrolithotomy.
Category
Treatment - Drugs

Recruitment centers

1

Recruitment center
Name of recruitment center
Shahid Beheshti Hospital
Full name of responsible person
Dr Mahmood Ebrahimi
Street address
Shahid Beheshti Hospital, Eram Ave.
City
Hamadan

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Full name of responsible person
Dr Saeid Bashirian
Street address
Hamadan University of Medical Sciences, Shahid Fahmideh Ave
City
Hamadan
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Beheshti Hospital
Full name of responsible person
Dr Mahmood Ebrahimi
Position
Resident of Urology
Other areas of specialty/work
Street address
Shahid Beheshti Hospital, Eram Ave.
City
Hamadan
Postal code
Phone
+98 81 3838 0283
Fax
Email
drmebrahimi22@yahoo.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Beheshti Hospital
Full name of responsible person
Dr Habibolah Moosavi Bahar
Position
Urologist
Other areas of specialty/work
Street address
Shahid Beheshti Hospital, Eram Ave.
City
Hamadan
Postal code
Phone
+98 81 3838 0283
Fax
Email
shmbahar@umsha.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Department of Epidemiology
Full name of responsible person
Dr Jalal Poorolajal
Position
Associate Professor
Other areas of specialty/work
Street address
School of Public Health, Hamadan University of Medical Sciences, Shahid Fahmideh Ave
City
Hamadan
Postal code
6517838695
Phone
+98 81 3838 0090
Fax
Email
poorolajal@umsha.ac.ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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