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Study aim:
Comparison of the effect of acetylcysteine and bromhexine on the improvement and prevention of hospitalization in outpatients
Design:
One group of patients will be given oral acetylcysteine 600 mg twice daily for 5 days and another group will be given 8 mg bromhexine tablets three times daily for 5 days. Referral, on day 7 and day 14, patients' oxygen levels and hospitalization and death are checked.
Settings and conduct:
This double-blind clinical trial is performed on 92 outpatients referred to Dibaj Municipal Services Center. The diagnosis of Covid-19 is debugged at the health service center and the patient enters the study after the test is confirmed. First, the blood oxygen level of the patients was measured with a pulse oximeter and from 92 patients, they were randomly assigned to group A and the rest to group B, and then to a group of patients taking oral acetylcysteine 600 mg twice daily. For 5 days, the other group is given 8 mg of bromhexine tablets three times a day for 5 days. Then, on day 7 and day 14, the patients are followed up and the patients' blood oxygen saturation level is measured and recorded with a pulse oximeter.
Participants/Inclusion and exclusion criteria:
Inclusion criteria include:
• Adult patients aged 18 to 70 years referred to Dibaj Municipal Service Center
• Outpatients with Covid-19 symptoms after positive Covid-19 RT-PCR test
• Oxygen level 98-92%
Exclusion criteria:
• Pregnancy and lactation
.Patients taking nitroglycerin.
Intervention groups:
This clinical trial is performed on outpatients Covid 19. One group of patients is given oral acetylcysteine 600 mg twice daily for 5 days and another group is given 8 mg bromhexine tablets three times daily for 5 days. On the day of referral, day 7 and day 14, patients' oxygen levels and their hospitalization and death are checked.
Main outcome variables:
Duration of recovery, Duration of hospitalization, Death