IRCT201405181597N3 IRCT 2014-06-16 Shahid Beheshti University of Medical Sciences and Health Services Effect of Probiotics on diabetes mellitus arising in pregnancy Effect of Probiotics in comparison with placebo on glucose metabolism, weight changes and inflammatory and oxidative stress indices in women with gestational diabetes mellitus 2014-05-29 anticipated 64 Complete https://irct.ir/trial/1005 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: Patients will be randomly included in intervention and control groups through sequential matching based on pre-pregnancy body mass index (18.5 to 24.9, 25 to 29.9 and 30 and more kilograms per square meter) and fasting plasma glucose (92 to 104 and 105 and more milligrams per deciliter). 2 Gestational Diabetes Mellitus. Intervention 1: Control: in control group, 32 pregnant women after the entry qualifications, will take one tablet of placebo with the shape and color exactly similar to 4biocap for 8 weeks and variables will be analyzed before and after the intervention. Intervention 2: Intervention: in intervention group, 32 pregnant women after the entry qualifications will take one capsule of 4biocapⓇ containing 180 mg(>1 billion CFU) of a standardized, cream colored powder consisting of freeze-dried cultures of: Lactobacillus Acidophilus LA-5Ⓡ, Bifidobacterium, BB-12Ⓡ, Streptococcus Thermophilus, STY-31 and Lactobacillus Delbrueckii ssp. Bulgaricus, LBY-27, once a day for 8 weeks and variables will be analysed before and after the intervention.