IRCT201205279875N1 IRCT 2014-03-01 Cinnagen Drug Corporation The comparison of effects of two drugs in neutropenic patients The comparison of effects of Filgrastim and Peg-Filgrastim in neutropenic patients 2012-09-01 anticipated 66 Complete https://irct.ir/trial/10412 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Treatment, Other design features: Patients, drug injectors and physicians were aware of the drug is injected. There was no possibility blinding of the groups due to difference in drug injection days. Groups participating in the study were three different groups include 11 subjects were selected from each group. The randomizing in our study is unenforceable. In this study, 33 patients were enrolled in three different groups according to underlying disease. The patients at two different times under two different treatment and self control groups were considered as individual. Thus overall sample size in this study is equal to 66. 2-3 Neutropenia. Intervention 1: Filgrastim, subcutaneously, 5-10 µg/kg, daily, to 7 days. Intervention 2: Pegfilgrastim, Ampule subcutaneously,100 µg/kg as a single dose.