IRCT2012061910068N1 IRCT 2012-07-05 Shahid Beheshti University of Medical Science Labor induction in term pregnant women of with oral misoprostol or oxytocin Induction and augmentation of labor with oral misoprostol versus oxytocin in term pregnancy: randomized controlled trial 2008-01-01 anticipated 285 Complete https://irct.ir/trial/10549 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 0 (exploratory trials) labor induction. Intervention 1: In the oxytocin group, infusion rate of 2 mIU/min was prescribed for induction and gradually increased by 2 mIU/min every 15 minutes to a maximum dose of 36 mIU/min. In presence of any tachysystole (5 contractions in a 10-minute interval) or hypertonus (single contractions lasting 2 minutes or longer), or changes in fetal heart rate associated with tachysystole or hypertonus, infusion rate was decreased or stopped. Intervention 2: Initiation of labor induction was the time at which the first misoprostol dose was administered (group 1) or the oxytocin infusion was started (group 2). In the misoprostol group, a tablet of 200 µg was dissolved in 200cc of water and 25cc was administered every two hours for up to 24 hours (10). The maximum dose was 300 µg. If the ideal pattern of contractions (at least 3 contractions per 10 minutes) was reached, misoprostol was no longer administered. ّFetal heart monitoring and uterine contraction were also recorded.