IRCT2012103111339N1 IRCT 2012-12-06 Arak University of Medical Sciences Montelukast effect in the prevention of respiratory infections Comparison of Montelukast and placebo in the prevention of upper respiratory infections in children 1 to 5 years 2012-11-21 anticipated 380 Complete https://irct.ir/trial/11607 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A Common cold. Intervention 1: In this randomized, double-blind study 190 children from 1 to 5 years old referred to Pediatric Clinic of arak Amir Kabir Hospital from 21/11/2012 to 19/2/2013 who do not have hyper reactive airway disease get montelucast(5 mg daily) oral once a day and fills for them an information form then they followed by weekly calls.In addition, each patient Receives a record sheet of fever, rhinitis, cough, antipyretic or antibiotic use, the absence of child care and doctor visits.Each patient will be followed for 12 weeks. Intervention 2: In this randomized, double-blind study 190 children from 1 to 5 years old referred to Pediatric Clinic of arak Amir Kabir Hospital from 21/11/2012 to 19/2/2013 who do not have hyper reactive airway disease get placebo oral once a day and fills for them an information form then they followed by weekly calls.In addition, each patient Receives a record sheet of fever, rhinitis, cough, antipyretic or antibiotic use, the absence of child care and doctor visits.Each patient will be followed for 12 weeks.