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IRCT2012110811389N2 IRCT 2012-12-24 Vice Chancellor for Research , Hamedan University of Medical Sciences Therapeutic effect of Montelukast in patients with oral lichen planus Evaluation of therapeutic effect of Montelukast and Prednison in patients with oral lichen planus 2013-01-04 anticipated 200 Complete https://irct.ir/trial/11650 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: single blinded: only the practitioner knows the therapeutic process . Randomization : Stratified - Blocking. 3 Lichen Planus. Intervention 1: Montelukast , 10 milligrams oral tablet , first month : daily, one tablet and second month : alternate day, one tablet. Intervention 2: Placebo ,10 milligrams oral tablet , similar motelukast , first month : daily , one tablet and second month : alternate day , one tablet.
public Hossein Hasannia
Dentistry Faculty ، Hamedan University of Medical Sciences , Shahid Fahmideh St. , Hamedan , Iran
Hamedan Iran (Islamic Republic of) 6517774433 +98 81 1839 0936 dr_hossein78@yahoo.com Hamedan Dentistry Faculty scientific Poorandokht Davoodi
Dentistry Faculty ,Hamedan University of Medical Sciences , Shahid Fahmideh St. , Hamedan , Iran
Hamedan Iran (Islamic Republic of) 6517838677 +98 81 1825 0998 p.davoodi@umsha.ac.ir Hamedan Dentistry Faculty Iran (Islamic Republic of) Inclusion criteria : (1) Diagnosis of OLP will be carried out by clinical history , physical exams and histopathological findings. (2) All of the patients should not use medication for at least two months. (3) They should not have systemic diseases such as diabetes mellitus, hepatitis and trauma history. Exclusion criteria : Patient is non-compliant with treatment until end of study. 40 years 55 years Both L43 Lichen Planus Treatment - Drugs Placebo Montelukast , 10 milligrams oral tablet , first month : daily, one tablet and second month : alternate day, one tablet Placebo ,10 milligrams oral tablet , similar motelukast , first month : daily , one tablet and second month : alternate day , one tablet Size of lesion. Timepoint: Study onset/after 2,4,6,8,10,12 weeks. Method of measurement: Ruler or flexible surgical probe. Pain rate. Timepoint: Study onset/after 2,4,6,8,10,12 weeks. Method of measurement: Visual Analogue Scaling. Vice Chancellor for Research , Hamedan University of Medical Sciences Approved 2012-08-13 Ethics Committee of Hamedan University of Medical Sciences Vice Chancellor for research , Hamedan University of Medical Sciences , Shahid Fahmideh St. , Hamedan , Iran Hamedan Iran (Islamic Republic of)