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IRCT2012110811408N1 IRCT 2013-01-30 Vice Chancellor for Research and Technology of Hamadan University of Medical Sciences and Health ser Evaluating the changes in outcome and serum metabolic biochemical parameters after oral Simvastatin administration in patients with poly cystic ovary syndrome undergoing IVF Oral simvastatin effect on reproductive outcomes and biochemical metabolic parameters in PCOS patients undergoing IVF 2013-02-19 anticipated 40 Complete https://irct.ir/trial/11686 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Used, Assignment: Single, Purpose: Treatment. N/A Poly Cystic Ovarian Syndrom. Intervention 1: Tab Simvastatin group 20 mg daily and Tab Metformin 500 mg daily for 8 week. Intervention 2: Tab Metformin 500 mg daily for 8 week.
public Dr Somayeh Enayati
Fatemiyeh Hospital, Kermanshah Street, Hamadan
Hamadan Iran (Islamic Republic of) +218 8968966 somayeh2.enayati@gmail.comsampad.hamedan@gmail.com Hamadan University of Medical Sciences and Health services scientific Dr Somayeh Enayati
Fatemiyeh Hospital, Kermanshah Street, Hamadan
Hamadan Iran (Islamic Republic of) +218 8968966 somayeh2.enayati@gmail.comsampad.hamedan@gmail.com Hamadan University of Medical Sciences and Health Servises Iran (Islamic Republic of) inclusion criteria: All patients in reproductive age with pcos that refer to infertility clinic of fatemieh hospital of Hamadan, that agreed to participate in the study and complete the informed consent, and without history of endocrine disease, Recent use of lipid-lowering drugs and statins. exclusion criteria: don't referring After getting treatment, arbitrary discontinuation of treatment 15 years 45 years Female E28.2 Sclerocystic ovary syndrome Treatment - Drugs Treatment - Drugs Tab Simvastatin group 20 mg daily and Tab Metformin 500 mg daily for 8 week Tab Metformin 500 mg daily for 8 week HDL. Timepoint: before of study and the fourth and eighth weeks. Method of measurement: with Biochemical laboratory techniques and in mg per deciliter. LDL. Timepoint: before of study and the fourth and eighth weeks. Method of measurement: with Biochemical laboratory techniques and in mg per deciliter. TG. Timepoint: before of study and the fourth and eighth weeks. Method of measurement: with Biochemical laboratory techniques and in mg per deciliter. Testestroon. Timepoint: before of study and the fourth and eighth weeks. Method of measurement: with Biochemical laboratory techniques and in mg per deciliter. GTT. Timepoint: before of study and the fourth and eighth weeks. Method of measurement: with Biochemical laboratory techniques and in mg per deciliter. Vice Chancellor for Research and Technology of Hamadan University of Medical Sciences and Health ser Approved 2012-08-16 ethics committee of Hamadan University of Medical Sciences Hamadan- mahdiyeh Street - Hamadan University of Medical Sciences - Department of Research and Technology - Office of the Ethics Committee of the University hamadan Iran (Islamic Republic of)