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IRCT2014040511662N6 IRCT 2014-05-23 Vice-Chancellery of Research and Technology Comparison of the analgesic effect of magnesium and Tramadol after local anesthesia of upper extremity. Comparison of the Efficacy of Magnesium sulfate and Tramadol as an adjunct to the Intravenous Regional Block for Controlling Postoperative Pain Following Upper Extremity Surgeries. 2014-06-22 anticipated 69 Complete https://irct.ir/trial/11835 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Acute Postoperative Pain. Intervention 1: Control group: 10 cc saline in the 10 ml syringe will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe. Intervention 2: Interventional group 1: 1.5 gram magnesium sulfate diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe . Intervention 3: Interventional group 2 : 100 miligram tramadol diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe .
public Mohammad Ali Sahmeddini
Shiraz Anesthesiology and Critical Care Research Center, Namazi Hospital, Namazi Sq.
Shiraz Iran (Islamic Republic of) 7193711351 +98 71 1647 4270 sahmeddini@sums.ac.ir Shiraz University Of Medical Sciences scientific Mohammad Ali Sahmeddini
Shiraz Anesthesiology and Critical Care Center, Namazi Hospital, Namazi Sq
Shiraz Iran (Islamic Republic of) 7193711351 +98 71 1647 4270 sahmeddini@sums.ac.ir Shiraz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: 69 patients 15-65 years old with ASA 1&2candidates for elective hand and forearm surgery or due to trauma. Exclusion criteria: History of drug abuse; History of allergies to drugs such as local anesthetics or opioid; History of: liver diseases; cardiovascular disease; renal failure; sickle cell anemia; Raynaud's disease; coagulopathy; G6PD deficiency; seizures. 15 years 65 years Both R52.0 Acute pain Treatment - Drugs Treatment - Drugs Treatment - Drugs Control group: 10 cc saline in the 10 ml syringe will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe Interventional group 1: 1.5 gram magnesium sulfate diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe . Interventional group 2 : 100 miligram tramadol diluted with saline to a volume of 10 cc will be injected into the patient by a resident of anesthesia who will not aware of the content of 10 cc syringe . Postoperative pain intensity. Timepoint: Every hour for 6 hours and then every 4 hours for 24 hours after surgery. Method of measurement: Visual Anlouge Scale. Nausea and Vomiting. Timepoint: Every one hour during first postoperative 24 hr. Method of measurement: Nausea is defined as urge to vomiting without ejection ofof the contents of the stomach through the mouth, Vomiting is defined asto eject of the contents of the stomach through the mouth, usually in a series of involuntary spasmic movements. Vice-Chancellery of Research and Technology Approved 2014-03-09 Shiraz University Medical Research Ethic Committee Shiraz University of Medical Sciences ,Zand Blv Shiraz Iran (Islamic Republic of)