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IRCT2014110612146N5 IRCT 2014-12-04 Vice chancellor for Research, Tabriz University of Medical Sciences Assessment of intrauterine injection of human Chorionic Gonadotropin (hcg) before transferring of Frozen-Thawed embryo on Implantation and clinical pregnancy rate Assessment of intrauterine injection of human Chorionic Gonadotropin (hcg) before transferring of Frozen-Thawed embryo on Implantation and clinical pregnancy rate 2014-11-19 anticipated 100 Complete https://irct.ir/trial/12270 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Female Infertility. Intervention 1: In the intervention group, five thousand units of hCG in a vial with 0.4 ml of ISM1 mixed media and 40 microliter of which is equivalent to 500 IU hCG injected through the catheter into the uterus. Seven minutes after the injection of hCG into the uterine, depending on the age and general condition of the fetus figure 2-3 embryos are transferred into the uterus. Intervention 2: In the control group, if endometrial thickness to achieve eight millimeters or more injections of progesterone injected intramuscularly at a dose of fifty milligrams per day.Transfer Eight-cell embryo three days after receiving progesterone and received five days after blast cyst transfer is planned.
public Dr. Farzadi Laaya
Tabriz University of Medical Sciences, Golgasht Street
Tabriz Iran (Islamic Republic of) +98 41 3556 9543 lahroudin@gmail.com; wrhrcenter@gmail.com Tabriz University of Medical Sciences scientific Dr. Farzadi Laaya
Tabriz University of Medical Sciences, Golgasht Street
Tabriz Iran (Islamic Republic of) +98 41 3556 9543 lahroudin@gmail.com; wrhrcenter@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: patients younger than 40 years old who underwent treatment protocols for IVF (ISCT) however, due to the unsuitable conditions in their endometrium embryo transfer cycles done in fresh or pregnancy occurred; patients with frozen embryos. Exclusion criteria: patients with a history of uterine surgery; recurrent abortions; hydrosalpinges; endometriosis and endometriomas. no limit 40 years Female N97 Female infertility Treatment - Drugs Treatment - Drugs In the intervention group, five thousand units of hCG in a vial with 0.4 ml of ISM1 mixed media and 40 microliter of which is equivalent to 500 IU hCG injected through the catheter into the uterus. Seven minutes after the injection of hCG into the uterine, depending on the age and general condition of the fetus figure 2-3 embryos are transferred into the uterus. In the control group, if endometrial thickness to achieve eight millimeters or more injections of progesterone injected intramuscularly at a dose of fifty milligrams per day.Transfer Eight-cell embryo three days after receiving progesterone and received five days after blast cyst transfer is planned. Positive Pregnancy Test. Timepoint: Two weeks after embryo transfer. Method of measurement: Test βhCG. Gestational sac. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound. The number of bags. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound. Fetal pole. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound. Embryo heart. Timepoint: Three weeks after embryo transfer. Method of measurement: Primary vaginal ultrasound. Vice chancellor for Research, Tabriz University of Medical Sciences Approved 2014-10-09 Tabriz University of Medical Sciences Golgasht Street ,Tabriz University Of Medical Sciences Tabriz Iran (Islamic Republic of)