<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT2013022112551N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2014-01-15</date_registration>
      <primary_sponsor>Isfahahan University of Medical Sciences</primary_sponsor>
      <public_title>effect of Exercise on coronary artery disease risk factors</public_title>
      <acronym></acronym>
      <scientific_title>The effect of resistance exercise on  coronary artery disease risk factorsin the patients referred to Isfahan Cardiovascular Research center</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2013-04-09</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>40</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/12603</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive.</study_design>
      <phase>N/A</phase>
      <hc_freetext>coromary artery disease.</hc_freetext>
      <i_freetext>Intervention 1: 20 eligible subjects assigned randomly to intervention group.&#13;
In the intervention group, one day before the beginning of the intervention, Demographic data was collected. Blood pressure was measured and recorded. Blood sampling was taken for fasting blood sugar and lipid profile measurement. One day after the end of the intervention&#13;
 blood pressure , fasting blood sugar and lipid profile was controlled.&#13;
During the study period of 8 weeks, all the study subjects participated two exercise sessions last 45-60 minutes, per week.&#13;
in the intervention group, in addition to routine exercise, resistance exercise was performed too: at the first session of the intervention, the weight was determined. At the start, the numbers of repetitions in the range of motion were considered 10 repetitions that increased gradually to 15 repetitions. After the each set of 15 repetitions, the amount of weight( 3-5 percent) and number of sets raised. Intervention 2: 20 eligible subjects assigned randomly to control group.&#13;
In the control group, one day before the beginning of the intervention, Demographic data was collected. Blood pressure was measured and recorded. Blood sampling was taken for fasting blood sugar and lipid profile measurement. One day after the end of the intervention&#13;
 blood pressure , fasting blood sugar and lipid profile was controlled.&#13;
During the study period of 8 weeks, all the study subjects participated two exercise sessions last 45-60 minutes, per week. &#13;
The control group followed routine rehabilitation unit protocol that was aerobic exercise.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan></results_IPD_plan>
      <results_IPD_description></results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Zahra Salehi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Isfahan University of Medical Sciences,Hezar Jerib Ave</address>
        <city>Isfahan</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 33 4243 2929</telephone>
        <email>z_salehi@nm.mui.ac.ir</email>
        <affiliation>Isfahan University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Zahra Salehi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Isfahahan University of Medical Sciences,Hezar Jerib Avenue</address>
        <city>Isfahahan</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip></zip>
        <telephone>+98 33 4243 2929</telephone>
        <email>z_salehi@nm.mui.ac.ir</email>
        <affiliation>Isfahan University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Iinclusion criteria: Patients referring to the Isfahan Cardiovascular Research center; being pre-hypertensive;stage1 hypertensive  ; taking lowering blood pressure drugs;  history of myocardial infarction prior 2 months, ten days after coronary angioplasty;3 months after heart bypass surgery &#13;
Exclusion criteria: Smoking; professional in exercise; participation in an exercise program during the last 3 months; absence for more than three consecutive meetings rehabilitation program; the incidence of acute conditions associated with health; limitations to exercise</inclusion_criteria>
      <agemin>no limit</agemin>
      <agemax>no limit</agemax>
      <gender>Both</gender>
      <exclusion_criteria></exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>I25.1</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Atherosclerotic heart disease</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>20 eligible subjects assigned randomly to intervention group.&#13;
In the intervention group, one day before the beginning of the intervention, Demographic data was collected. Blood pressure was measured and recorded. Blood sampling was taken for fasting blood sugar and lipid profile measurement. One day after the end of the intervention&#13;
 blood pressure , fasting blood sugar and lipid profile was controlled.&#13;
During the study period of 8 weeks, all the study subjects participated two exercise sessions last 45-60 minutes, per week.&#13;
in the intervention group, in addition to routine exercise, resistance exercise was performed too: at the first session of the intervention, the weight was determined. At the start, the numbers of repetitions in the range of motion were considered 10 repetitions that increased gradually to 15 repetitions. After the each set of 15 repetitions, the amount of weight( 3-5 percent) and number of sets raised</i_keyword>
      <i_keyword>20 eligible subjects assigned randomly to control group.&#13;
In the control group, one day before the beginning of the intervention, Demographic data was collected. Blood pressure was measured and recorded. Blood sampling was taken for fasting blood sugar and lipid profile measurement. One day after the end of the intervention&#13;
 blood pressure , fasting blood sugar and lipid profile was controlled.&#13;
During the study period of 8 weeks, all the study subjects participated two exercise sessions last 45-60 minutes, per week. &#13;
The control group followed routine rehabilitation unit protocol that was aerobic exercise</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Mean blood pressure. Timepoint: The bigining and the end of the intervention. Method of measurement: Mmhg- Sphygmomanometer.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Fasting blood sugar. Timepoint: The bigining and the end of the intervention. Method of measurement: Mg/ dl. Iaboratory measuerments.</sec_outcome>
      <sec_outcome>Lipid profile. Timepoint: The bigining and the end of the intervention. Method of measurement: Mg/ dl. Iaboratory measuerments.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Isfahahan University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2013-04-30</approval_date>
        <contact_name>Isfahahan University of Medical Sciences</contact_name>
        <contact_address>Isfahahan University of Medical Sciences,Hezar Jerib Avenue , Isfahahan  Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
