]>
IRCT2013022512593N1 IRCT 2013-12-04 Ahvaz Jundishapur University of Medical Sciences (AJUMS) Reducing the acute pain and the need to narcotic pain relievers after cesarean surgery A comparison of the effects of diclofenac sodium suppositories, intravenous paracetamol and the combination of diclofenac sodium suppositories and intravenous paracetamol on reducing the acute pain and the need to narcotic pain relievers after cesarean surgery under spinal anesthesia 2013-04-21 anticipated 99 Complete https://irct.ir/trial/12638 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A cesarean surgery. Intervention 1: Second group will receive 1 gr intravenous paracetamol in 500 cc normal saline while entering the recovery and then they will receive 3gr intravenous paracetamol via PCA pomp plus one placebo suppository while leaving the recovery room. Intervention 2: First group will receive 100 mg Diclofenac sodium suppositories when entering the recovery and then they will receive 100 cc Normal saline via PCA pomp. Intervention 3: Third group will receive 1 gr intravenous paracetamol in 500 cc normal saline while entering the recovery and then they will receive 3gr intravenous paracetamol via PCA pomp plus a diclofenac 100 mg suppository.
public Dr. Gholamreza Safari Hezarvand
Golestan bulevard, University Pardise,
Ahvaz Iran (Islamic Republic of) +98 61 1332 3175 safari.r@ajums.ac.irreza.safari79@gmail.com Ahvaz Jundishapur University of Medical Sciences (AJUMS) scientific Dr. Gholamreza Safari Hezarvand
Golestan bulevard, unevrsity pardis,
Ahvaz Iran (Islamic Republic of) +98 61 1332 3175 safari.r@ajums.ac.irreza.safari79@gmail.com Ahvaz Jundishapur University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Being in ASA class 1 or 2; Being in ages between 18-35; Being first or second pregnancy. Exclusion criteria: Having any known allergies and sensitivities, banned from narcotic drugs, paracetamol, and NSAIDs; Hepatic Dysfunction (transaminaze twice than upper limit of normal level); Kidney dysfunction (plasma creatinine higher than 2.5 mg/dl); Smoking or having any previous pulmonary disease; Drug, narcotic, and alcohol abuse; Subjects with the history of depression or chronic anxiety; Subjects experienced the side effects of spinal anesthesia: back pain, radicular pain, paresthesia and hypoesthesia, PDPH; Spinal contraindication; Contraindications for the Use of Spinal Anesthesia (Patient decline, infection in the spot for entering the needle, high intracranial pressure, bleeding susceptibility). 18 years 45 years Female O32 Maternal care for known or suspected malpresentation of fetus Treatment - Drugs Treatment - Drugs Treatment - Drugs Second group will receive 1 gr intravenous paracetamol in 500 cc normal saline while entering the recovery and then they will receive 3gr intravenous paracetamol via PCA pomp plus one placebo suppository while leaving the recovery room. First group will receive 100 mg Diclofenac sodium suppositories when entering the recovery and then they will receive 100 cc Normal saline via PCA pomp. Third group will receive 1 gr intravenous paracetamol in 500 cc normal saline while entering the recovery and then they will receive 3gr intravenous paracetamol via PCA pomp plus a diclofenac 100 mg suppository Patient reported pain level. Timepoint: 1, 4, 12, and 24 hours after surgery. Method of measurement: Visual Analog Scale for Pain (VAS Pain). Intravenous Morphine. Timepoint: in periods of 0-4; 4-12; and 12-24 hours after surgey. Method of measurement: intravenous morphine dose (mg/kg). Ahvaz Jundishapur University of Medical Sciences (AJUMS) Approved 2013-09-28 morality in research committee Ahvaz Jondishapur University of medical Sciences Ahvaz Iran (Islamic Republic of)