IRCT2013040812758N2 IRCT 2013-05-01 Iraqi Board for Medical Specializations Treatment of acne vulgaris Topical Adapalene 0.1% Gel versus Topical Combination of (Tretinoin 0.025% and Erythromycin 4%) Gel in Treatment of AcneVulgaris 2009-10-01 anticipated 36 Complete https://irct.ir/trial/12757 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Acne vulgaris. A split face method for application of treatment will used in which each patient instructed to use a combined gel formula of tretinoin 0.025% and erythromycin 4% on the right side of the face and adapalene 0.1% gel on the left side..

public Dr.Husam Ali Salman

Medical collection office, P.O. Box 61211

baghdad Iraq 12114 00 husjob2000@yahoo.com Department of Dermatology-Baghdad medical college scientific Dr.Ammar Faisal Hameed

Medical city61106

Baghdad Iraq 00 amar@uobaghdad.edu.iq Department of Dermatology-Baghdad University Iraq Inclusion criteria: All patients with mild to moderate acne vulgaris will enrolled in the study. All patients must without any systemic and / or topical treatment for at least 2 months before starting the study. Exclusion criteria: Patients excluded from the study were those with severe acne, nodulocystic acne, patients with systemic diseases, pregnant and lactating women. no limit no limit Both L70.0 Acne vulgaris Treatment - Drugs A split face method for application of treatment will used in which each patient instructed to use a combined gel formula of tretinoin 0.025% and erythromycin 4% on the right side of the face and adapalene 0.1% gel on the left side. Change in acne scoring.(mild,moderate,severe)Mild acne in which the count of pustules is less than 20 and the count of papules is less than 10. Timepoint: Each patient was instructed to use the same amount of both gels (finger tip method), ½ hour in the 1st night then wash and increase the time by ½ hour in the successive nights till reach 8 hours; thereafter to keep the applications till morning. The duration of therapy was 6 weeks and follow up for another 6weeks. Method of measurement: The clinical evaluation was done every 3 weeks by 2 dermatologists; the assessment was carried out by counting the inflammatory lesions (papules and pustules) and watching any local side effects. The satisfaction of the patient with the treatment. Timepoint: The clinical evaluation was done every 3 weeks. Method of measurement: The satisfaction of the patients to the treatment is classified into:1- Full satisfaction.2- Partial satisfaction.3 - No satisfaction. Iraqi Board for Medical Specializations Approved 2009-08-02 Iraqi Board for Medical specializations Medical Collection Office, P.O. Box 61080 Postal Code 12114, Baghdad Iraq