]>
IRCT2014121712789N10 IRCT 2015-05-29 Vice Chancellor for Research, Kurdistan University of Medical Sciences Comparing the High Flux versus Low Flux membranes Comparing the effect of High Flux versus Low Flux membranes on the level of parathyroid hormone in patients with secondary hyperparathyroidism undergoing chronic dialysis 2014-12-22 anticipated 40 Complete https://irct.ir/trial/12798 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: To make the study double blind, blood sample taking and sending the blood samples to laboratory was done by one of the colleagues working in dialysis ward. Also patients were not aware of their grouping and the kind of membrane used for their hemodialysis. 3 Secondary hyperparathyroidism, not elsewhere classified. Intervention 1: In the intervention group, patients who have been on dialysis with Low Flux membrane for three years would be on dialysis for three months with High Flux membrane. Intervention 2: In the control group, patients who previously had been dialyzed by Low Flux membrane for three years would be dialyzed again for three months using Low Flux membrane .
public Rasol Azimi
Tohid Hospital, Basij Sq., Geriashan St., Sanandaj, Iran
Sanandaj Iran (Islamic Republic of) +98 87 3328 8119 rasoulazimi18@gmail.com Kurdistan University of Medical Sciences scientific Shahdak Dadashpour
Tohid Hospital, Basij Sq., Geriashan St., Sanandaj, Iran
Sanandaj Iran (Islamic Republic of) +98 87 3328 8119 shahdakdadashpour@yahoo.com Kurdistan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria included high level serum of parathyroid hormone (greater than 300pg / dl), performing dialysis by fixed means, dialysis three times a week for four hours, the patient should be at least 6 months on dialysis program, previous use of the Low Flux membrane, bearing on dialysis, age greater than 18 years, the ability to participate in the study. Exclusion criteria included; patients with acute renal failure, patients with poor vascular access that may affect their quality of dialysis , age less than 18 years, the continued lack of patient cooperation, discontinuation of dialysis for any reason, being dialysis by High Flux membrane previously 18 years 65 years Both N25.8 secondary hyperparathyroidism of renal origin Treatment - Other Treatment - Other In the intervention group, patients who have been on dialysis with Low Flux membrane for three years would be on dialysis for three months with High Flux membrane. In the control group, patients who previously had been dialyzed by Low Flux membrane for three years would be dialyzed again for three months using Low Flux membrane . Level serum of parathyroid hormone. Timepoint: Beginning of the study - Three months after the study. Method of measurement: ELISA method. Serum levels of phosphorus. Timepoint: Beginning of the study -Three months after the study. Method of measurement: The Prestige 24i Automated Analyzer. Hemodialysis Adequecy. Timepoint: Beginning of the study -Three months after the study. Method of measurement: kt/v method. Vice Chancellor for Research, Kurdistan University of Medical Sciences Approved 2014-09-03 Ethics Committee of Kurdistan University of Medical Sciences Kurdistan University of Medical Sciences, Pasdaran St., Sanandaj, Iran Sanandaj Iran (Islamic Republic of)