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IRCT2013043013181N1 IRCT 2013-09-11 Isfahan university of medical science Effect of continues positive airway pressure on de-airing process. Comparative evaluation of the effects of continuous positive airway pressure and zero airway pressure during cardiopulmonary bypass on cardiac de-airing after open heart surgery in patients with rheumatic heart valves diseases. 2012-03-19 anticipated 40 Complete https://irct.ir/trial/13128 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A cardiac chamber de-airing. Intervention 1: After turning the ventilator off, the flow of oxygen flow was maintained at the rate of 0.5L/min and the APL valve was placed in “Man” position on 20 mbar (20 hectopascal, 15mmHg). Intervention 2: During the surgery and CPB, the ventilator (Drager, Fabius) was turned off and the flow of fresh air was totally ceased and adjustable pressure limit (APL) valve was placed in “Spont” position.
public Mijtaba Mansouri
Chamran Heart Hospital, Salman-e-farsi St
Isfahan Iran (Islamic Republic of) +98 31 1775 0252 mansouri@med.mui.ac.ir Isfahan Medical School scientific Mojtaba Mansouri
Chamran Heart Hospital, Salman-e-Farsi St.
Isfahan Iran (Islamic Republic of) +98 31 1260 0961 mansouri@med.mui.ac.ir Isfahan Medical School Iran (Islamic Republic of) Inclusion criteria: Patients candidate for aorta and/or mitral valve with/without tricuspid valve replacement surgery; Ejection fraction >40%; Patients without heart surgery; absence of history of dysphasia, odinophagia and previous oesophageal surgery. Exclusion criteria: Intra aortic balloon while weaning from CPB. 20 years 80 years Both I05, I06, Chronic rheumatic heart diseases Prevention Prevention After turning the ventilator off, the flow of oxygen flow was maintained at the rate of 0.5L/min and the APL valve was placed in “Man” position on 20 mbar (20 hectopascal, 15mmHg). During the surgery and CPB, the ventilator (Drager, Fabius) was turned off and the flow of fresh air was totally ceased and adjustable pressure limit (APL) valve was placed in “Spont” position. Time of de-airing. Timepoint: from mechanical ventilation bigining untill end of de-airing process. Method of measurement: minute. Amount of air bubble in left atrium cavity durig de-airing. Timepoint: from mechanical ventilation bigining untill end of de-airing process. Method of measurement: scale: mild, moderate, sever. Isfahan university of medical science Approved 2012-02-01 Isfahan univesity of medical science Isfahan, Hezar Jarib St. Isfahan Iran (Islamic Republic of)