IRCT201504251764N3 IRCT 2015-07-06 Vice chancellor for research,Tehran University of Medical Sciences Effect of Ketamine for pediatrics pain Efficacy and safety of oral low dose ketamine for pediatric Intravenous cannulation 2014-03-20 anticipated 70 Complete https://irct.ir/trial/1314 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 pain during Intravenous placement in pediatrics. Intervention 1: After obtaining consent from the parents of patients , patients are classified in two groups of intervention and control by permuted block randomization . Then for each group a questionnaire including demographic informations , age, gender, weight, chief complaint, ASA class, primary diagnosis, receiving concomitant medications, location of Intravenous placement and other required information are recorded. In the intervention group ketamine mixed in orange juice with dose of 3 mg/kg is given to patients orally one dose. after20- 30 minutes Intravenous placement is done and the pain of patients is measured with desired scales during the procedure. Intervention 2: After obtaining consent from the parents of patients , patients are classified in two groups of intervention and control by permuted block randomization . then for each group a questionnaire including demographic informations , age, gender, weight, chief complaint, ASA class, primary diagnosis, Receiving concomitant medications, location of Intravenous placement, duration of procedure, final diagnosis and other required information are recorded. in the control group,patients take only orange juice. after20- 30 minutes iv placement is done and the pain of patients is measured with desired scales during the procedure.