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IRCT2015021713566N3 IRCT 2015-05-29 Vice chancellor for Research,Tabriz University of Medical Sciences Study of injection of follicular fluid into uterine cavity on implantation rate in IVF cycle Study of injection of follicular fluid into uterine cavity on implantation rate in IVF cycle 2015-04-19 anticipated 110 Complete https://irct.ir/trial/13383 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Infertility. Intervention 1: In the control group: Antagonist protocol GnRH will be used to stimulate ovulation, HCG may be used to seeing at least three follicles larger than 18 mm. After 34 to 36 hours will puncture of ovarian follicles. Intervention 2: In the intervention group: Antagonist protocol GnRH will be used to stimulate ovulation, HCG may be used to seeing at least three follicles larger than 18 mm. After 34 to 36 hours will puncture of ovarian follicles. After isolation of the oocyte Part of follicular fluid from the puncture. Will be injected by intrauterine 2 cc of liquid by using IUI catheter after follicle puncture embryo transfer will take place two days after ovarian puncture.
public Dr. Kobra Hamdi
Golgasht Street, Tabriz University Of Medical Sciences
Tabriz Iran (Islamic Republic of) +98 41 3556 9543 hamdik@tbzmed.ac.ir; lahroudin@gmail.com Tabriz University of Medical Sciences scientific Dr. Kobra Hamdi
Golgasht Street, Tabriz University Of Medical Sciences
Tabriz Iran (Islamic Republic of) +98 41 3556 9543 hamdik@tbzmed.ac.ir; lahroudin@gmail.com Tabriz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: patients aged 20 to 40 years old; FSH levels below mIU / m l 10; BMI less than 35 kg /m2; transfer 2 or 3 embryos Grade A or B; Exclusion criteria: patients with endometriosis; hydrosalpinx; uterine anatomical abnormalities such as myoma; polyps; mullerian anomalies like two horns of the uterus; endocrine disorders such as thyroid disease; PCO and have a history of two or more implantation failure. 20 years 40 years Female N97.0 Female infertility associated with anovulation Treatment - Drugs Treatment - Drugs In the control group: Antagonist protocol GnRH will be used to stimulate ovulation, HCG may be used to seeing at least three follicles larger than 18 mm. After 34 to 36 hours will puncture of ovarian follicles In the intervention group: Antagonist protocol GnRH will be used to stimulate ovulation, HCG may be used to seeing at least three follicles larger than 18 mm. After 34 to 36 hours will puncture of ovarian follicles. After isolation of the oocyte Part of follicular fluid from the puncture. Will be injected by intrauterine 2 cc of liquid by using IUI catheter after follicle puncture embryo transfer will take place two days after ovarian puncture. Chemical Pregnancy. Timepoint: Measure B-HCG Sixteen days after injection of HCG. Method of measurement: ΒhCG test. Clinical pregnancy ( gestational sac seen by viewing the fetal heart rate and fetal pole. Timepoint: After positive βhCG. Method of measurement: Ultrasound. Implantation rates. Timepoint: Two weeks after a positive pregnancy test. Method of measurement: Ultrasound. Vice chancellor for Research,Tabriz University of Medical Sciences Approved 2015-05-16 Tabriz University of Medical Sciences Golgasht Street ,Tabriz University Of Medical Sciences Tabriz Iran (Islamic Republic of)