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IRCT2013112813828N5 IRCT 2014-03-18 Islamic Azad University, Najafabad Branch Effect of iron replacement therapy in patients with chronic heart failure and iron deficiency anemia Evaluation of the effect of iron replacement therapy on symptom and quality of life in patients with chronic heart failure and iron deficiency who referred to Isfahan's Shariarti hospital in 1392-93 2014-03-11 anticipated 46 Complete https://irct.ir/trial/13586 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A chronic heart failure. Before starting intervention hemoglobin level,serum iron,Toral iron binding capacity,transferrin saturation and ferritin will be measured.also patient's quality of life and 6 minute walk test will be measured.then iron depletion will be calculated then patients will be received 200 mg intravenous iron every week and after iron replacement therapy, patients will be reevaluated in terms of hemoglobin level,serum iron,total iron binding capacity,transferrin saturation. ferritin , patient's quality of life and 6 minute walk test..
public
scientific Dr.Mirdamadi
Sheikhbahaei Street, Isfahan Hospital,
Isfahan Iran (Islamic Republic of) +98 31 1233 0015 drsamirdamadi@yahoo.com Islamic Azad University, Najafabad Branch Iran (Islamic Republic of) Inclusion Criteria:patient's consent;patients with stable chronic heart failure;Iron deficiency anemia;Age between 30 and 75 years old exclusion criteria:No consent to participate in study;patient with unstable heart failure;Patient with hemoglobinopathy;Patient with B12 and follic acid deficiency;Pregnancy;Age less than30 or more than75 years old 30 years 75 years Both I50 Heart failure Treatment - Drugs Before starting intervention hemoglobin level,serum iron,Toral iron binding capacity,transferrin saturation and ferritin will be measured.also patient's quality of life and 6 minute walk test will be measured.then iron depletion will be calculated then patients will be received 200 mg intravenous iron every week and after iron replacement therapy, patients will be reevaluated in terms of hemoglobin level,serum iron,total iron binding capacity,transferrin saturation. ferritin , patient's quality of life and 6 minute walk test. 6 Minute Walk Test. Timepoint: Before intervention and also afte iron deficiency anemia treatmen. Method of measurement: This test measures the distance that a patient can quickly walk on a flat, hard surface in a period of 6 minutes. Quality Of Llife. Timepoint: Before intervention and also after iron deficiency anemia treatment. Method of measurement: Quality Of Llife Questionnaire. New York Heart Association Functional Classification. Timepoint: Before intervention and also afte iron deficiency anemia treatmen. Method of measurement: patient's words. Serum creatinine. Timepoint: before intervention and after iron deficiency anemia treatment. Method of measurement: jaffe. Glomerular filtration rate. Timepoint: before intervention and after iron deficiency anemia treatment. Method of measurement: (140-age)*mass(in kilogram)*(0.85 if female/72*serum creatinine(in mg/dl). Islamic Azad University, Najafabad Branch Approved 2014-02-06 Isfahan University Of Medical Sciences azadi square isfahan Iran (Islamic Republic of)