IRCT2014081714333N19 IRCT 2014-09-07 Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences The effect of general and epidural anesthesia on respiratory parameters during and after laparoscopic cholecystectomy surgery The effect of general and epidural anesthesia on respiratory parameters during and after laparoscopic cholecystectomy surgery 2014-06-15 anticipated 58 Complete https://irct.ir/trial/13955 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Laparascopic cholecystectomy. Intervention 1: In the first group(GA), After pre-medication among GA with midazolam 05.0 mg/kg, intravenous fentalyn 1 µg/kg, patients are anesthetized using propofol 2 mg/kg and atracurium 5.0 mg/kg and standard monitoring is completed. Proper indotratracheal tube is contrived and surgery starts. During the surgery, anesthetization continues through using isoflurane 1.4 1% blended with mixture of air and 50% oxygen. During the surgery ABG is tested and SPO2 is measured accordingly. An hour later, during recovery period, ABG is retested and VC and SPO2 are measured through monitoring. Intervention 2: In the second group (EA), 10 cc Lidocaine and epinephrine 1 in 200000, including 1 cc sodium bicarnonate for each 10 cc of Lidocaine, would be injected in the space between vertebrae of the thoracic using epidural set. ABG and SPO2 would be measured during surgery. ABG would be measured again, and VC and SPO2 would be checked using monitor an hour after surgery during recovery period.