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IRCT20130911014630N4 IRCT 2018-07-16 Mazandaran University of Medical Science- Sari - Mazandaran - Iran Evaluation of Gel Formulation of Trigonella foenum-graceum Seed on prevention of trichoptilosis in randomized placebo controlled Clinical Trial Evaluation of Gel Formulation of Trigonella foenum-graceum Seed on prevention of trichoptilosis in randomized placebo controlled Clinical Trial 2017-11-22 anticipated 60 Complete https://irct.ir/trial/14212 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Simple randomization, individual, using random numbers table, Blinding description: In this study, dermatologist, and dermatologist, as well as the placebo or drug product, have no information about the product and the products have been pre - determined and randomly assigned to the patients. N/A Trichoptilosis. Intervention 1: Intervention group: The gel contains 5 grams extract of seeds of fenugreek used Twice daily , so that the whole hair should be covered . Do not shave 12 hours after use .To this end, 30 patients are selected according to the conditions of entry.They are given the drug gel formulation containing fenugreek seed extract for two months under the supervision of a dermatologist and in collaboration with the presenter.Herbal gel contains 5% fenugreek seed extract.To prepare 100 cc of gel, 0.02 grams of propyl paraben, 0.18 grams of methyl paraben, 1 gram of carbapl 980, 5 milliliters of glycerin, Small amount of 1% NaOH solutionn and up to 100 cc of distilled water, UP is used. It is expected that the extract of Fenugreek seed with its effect on the cuticle structure of the hair will increase its strength and reduce the bulging of the ends of hair shafts. This gel was made in the lab of the Mazandaran -Sari Pharmaceutical Faculty. Intervention 2: Control group: The placebo gel contains all the ingredients of the drug gel except for the fenugreek seed extract.The method of use is the same as druged gel. It is used twice daily and Do not shave 12 hours after use.To this end, 30 patients are selected according to the conditions of entry.They are given the placebo gel formulation for two months under the supervision of a dermatologist and in collaboration with the presenter.It is expected that this gel does not have a significant effect, unlike the druged gel.This gel was made at the laboratory of the Mazandaran -Sari Pharmaceutical Faculty. Yes - There is a plan to make this available What will be shared: Results from clinical trials When: Start access after printing the article To whom: Access for scholars working in academic institutions Conditions: Use of results is allowed only by mentioning its source Where to obtain: azadbakhtm@hotmail.com How to obtain: Request from the researcher Comments:
public Majid Hajizadeh
Pharmacy College - Payambar Azam Medicinal Complex - Sari - Mazandaran - Iran
Sari Iran (Islamic Republic of) - 00 Majidhajizadeh_72@Yahoo.com Mazandaran University of Medicinal Science-Sari- Iran scientific Dr. Mohammad Azadbakht
Pharmacy College - Payambar Azam Medicinal Complex- Sari -Mazandaran -Iran
Sari Iran (Islamic Republic of) - 00 Mazadbakht@Mazums.ac.ir Mazandaran University of Medical Science-Sari Iran (Islamic Republic of) Inclusion criteria: Age 20-50 Man or woman Selection of patients without prior knowledge and based on their referral to a specialist physician The patient has an impairment trichoptilosis The patient has a disorder of personal satisfaction with the use of the product 20 years 50 years Both L67.8 Other hair colour and Hair shaft abnormalities Prevention Diagnosis Intervention group: The gel contains 5 grams extract of seeds of fenugreek used Twice daily , so that the whole hair should be covered . Do not shave 12 hours after use .To this end, 30 patients are selected according to the conditions of entry.They are given the drug gel formulation containing fenugreek seed extract for two months under the supervision of a dermatologist and in collaboration with the presenter.Herbal gel contains 5% fenugreek seed extract.To prepare 100 cc of gel, 0.02 grams of propyl paraben, 0.18 grams of methyl paraben, 1 gram of carbapl 980, 5 milliliters of glycerin, Small amount of 1% NaOH solutionn and up to 100 cc of distilled water, UP is used. It is expected that the extract of Fenugreek seed with its effect on the cuticle structure of the hair will increase its strength and reduce the bulging of the ends of hair shafts. This gel was made in the lab of the Mazandaran -Sari Pharmaceutical Faculty. Control group: The placebo gel contains all the ingredients of the drug gel except for the fenugreek seed extract.The method of use is the same as druged gel. It is used twice daily and Do not shave 12 hours after use.To this end, 30 patients are selected according to the conditions of entry.They are given the placebo gel formulation for two months under the supervision of a dermatologist and in collaboration with the presenter.It is expected that this gel does not have a significant effect, unlike the druged gel.This gel was made at the laboratory of the Mazandaran -Sari Pharmaceutical Faculty. Trichoptilosis. Timepoint: At least 2 times in week along 2 month. Method of measurement: Questionnaire. Calvities. Timepoint: At least 2 times in week along 2 month. Method of measurement: Questinnaire. Mazandaran University of Medical Science- Sari - Mazandaran - Iran Approved 2010-08-20 Ethics Commitee of Mazandaran University Of Medical Sciences Mazandaran University of Medical Sciences - Sari Sari Mazandaran Iran (Islamic Republic of)