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IRCT2013092214729N1 IRCT 2013-12-31 Vice chancellor for research, Kashan University of Medical Sciences Effect of mouth wash containing yarrow plant extract on improvement stomatitis Comparing the effect of mouth wash containing yarrow plant extract and routine solution on improvement stomatitis in cancer patients receiving chemotherapy 2013-10-01 anticipated 42 Complete https://irct.ir/trial/14277 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: In this study, the following people were blind and did not know of the contents two glass (glass 1: extract yarrow + 2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2% and glass 2: 2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2%) . 1) The person who gave the glass to the patient 2) A person who has examined the oral mucosa. 3) Patients. 0 (exploratory trials) Stomatitis. Intervention 1: Case 1: a experimental group solution containing extract yarrow-routine solution (2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2%) (glass 1) is given will. Patients 4 times a day, after breakfast, lunch, dinner and before sleeping, first, wash their hands, cleaning teeth with a soft toothbrush and one type of toothpaste, then 15 cc of the solution kept for 3 min in their mouth and then throw away. Patients should not wash their mouth, and refrain from consuming food until one hour after. According to a triple blind study, oral mucosa patients on the first, seventh and fourteenth days after getting mouthwash checked by a oncology nurse who does not know the mouthwash solution and then checklist is completed. Intervention 2: Case 2: a control group routine solution containing (2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2%) (glass 2) is given will. Patients 4 times a day, after breakfast, lunch, dinner and before sleeping, first, wash their hands, cleaning teeth with a soft toothbrush and one type of toothpaste, then 15 cc of the solution kept for 3 min in their mouth and then throw away. Patients should not wash their mouth, and refrain from consuming food until one hour after. According to a triple blind study, oral mucosa patients on the first, seventh and fourteenth days after getting mouthwash checked by a oncology nurse who does not know the mouthwash solution and then checklist is completed.
public Leyla Soleymanpoor
Kashan University of Medical Sciences
Kashan Iran (Islamic Republic of) 87155/111 +98 33 4635 2622 Leylalegla@yahoo.com Kashan University of Medical Sciences scientific Sedigheh Miranzadeh
Kashan - Ghotb Ravandi Blvd.
Kashan Iran (Islamic Republic of) 81755/111 +98 36 1555 2999 S_Miranzadeh@yahoo.com Kashan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criteria: informed consent for participation in the study, aged 20 years and older, no underlying disease (allergy, allergic rhinitis, asthma ), not receive radiation therapy after diagnosis, having consciousness, not use another mouthwash solution during the study, and not receiving systemic antibiotics and antifungals. Exclusion criteria: receiving radiotherapy during treatment, fever, use from another solution mouthwash during the study, the decision to withdraw from the study, irregular use of mouthwash solution (frequency, amount), solution containing extract yarrow odor intolerance by patients and received systemic antibiotics and antifungals at the beginning or during the study. 1 year 149 years Both k12.1 Stomatitis and related lesions Treatment - Drugs Treatment - Drugs Case 1: a experimental group solution containing extract yarrow-routine solution (2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2%) (glass 1) is given will. Patients 4 times a day, after breakfast, lunch, dinner and before sleeping, first, wash their hands, cleaning teeth with a soft toothbrush and one type of toothpaste, then 15 cc of the solution kept for 3 min in their mouth and then throw away. Patients should not wash their mouth, and refrain from consuming food until one hour after. According to a triple blind study, oral mucosa patients on the first, seventh and fourteenth days after getting mouthwash checked by a oncology nurse who does not know the mouthwash solution and then checklist is completed. Case 2: a control group routine solution containing (2 dexamethasone 8 mg, 5 tablets sucralfate 500 mg, 1 syrup diphenhydramine 12.5 mg, 1 injection of lidocaine 2%) (glass 2) is given will. Patients 4 times a day, after breakfast, lunch, dinner and before sleeping, first, wash their hands, cleaning teeth with a soft toothbrush and one type of toothpaste, then 15 cc of the solution kept for 3 min in their mouth and then throw away. Patients should not wash their mouth, and refrain from consuming food until one hour after. According to a triple blind study, oral mucosa patients on the first, seventh and fourteenth days after getting mouthwash checked by a oncology nurse who does not know the mouthwash solution and then checklist is completed. Stomatitis. Timepoint: Before and seventh and fourteenth days after the intervention. Method of measurement: Standardized checklist stomatitis WHO. Vice chancellor for research, Kashan University of Medical Sciences Approved 2013-09-30 Ethics committee of Kashan University of Medical Sciences Ghotb Ravandi Blvd Kashan Iran (Islamic Republic of)