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IRCT2013101214988N1 IRCT 2013-11-05 Vice chancellor for research, Tabriz University of Medical Sciences Comparison of two kind of drugs in the treatment of asthma Randomized clinical trial of comparing oral and inhalant corticosteroids in treatment of mild to moderate attack of asthma in children 2013-07-11 anticipated 60 Complete https://irct.ir/trial/14417 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Asthma. Intervention 1: First group will be treated with Salbutamol spray (2 puffs every four hours for 48 hours, each puff contains 100 micro grams of the drug) plus oral prednisolon (2 milligrams per each kilograms of body weight for one week). Intervention 2: Second group will be treated with Salbutamol spray (2 puffs every four hours for 48 hours, each puff contains 100 micro grams of the drug) plus Budesonide spray (2 puffs every 12 hours, for one week, each puff contains 200 milligrams of the drug).
public Dr. Masoumeh Ghasempour
Department of Pediatric diseases, Tabriz Children Hospital, Sheshgelan Street, Farmanfarmayan Street, Tabriz
Tabriz Iran (Islamic Republic of) +98 41 1526 2255 masoumeh_gh_a@yahoo.com Tabriz Children Hospital scientific Dr. Nemat Bilan
Department of Pediatric diseases, Tabriz Children Hospital, Sheshgelan Street, Farmanfarmayan Street, Tabriz
Tabriz Iran (Islamic Republic of) +98 41 1526 2255 Bilan@tbzmed.ac.ir Tabriz Children Hospital Iran (Islamic Republic of) Inclusion criteria: Having mild to moderate asthma attack; Age between 5 to 14 years old. Exclusion criteria: Unwillingness to participate in the study. 5 years 14 years Both J45 Asthma Treatment - Drugs Treatment - Drugs First group will be treated with Salbutamol spray (2 puffs every four hours for 48 hours, each puff contains 100 micro grams of the drug) plus oral prednisolon (2 milligrams per each kilograms of body weight for one week). Second group will be treated with Salbutamol spray (2 puffs every four hours for 48 hours, each puff contains 100 micro grams of the drug) plus Budesonide spray (2 puffs every 12 hours, for one week, each puff contains 200 milligrams of the drug) Forced expiratory volume in the first second. Timepoint: In the first and seventh day of the study. Method of measurement: By using spirometry device. FEV1/FVC. Timepoint: In the first and seventh day of the study. Method of measurement: By using spirometry device. Diurnal symptoms of the disease. Timepoint: In the first, third and seventh day of the study. Method of measurement: By examiner. Nocturnal symptoms of the disease. Timepoint: In the first, third and seventh day of the study. Method of measurement: By examiner. Vice chancellor for research, Tabriz University of Medical Sciences Approved 2013-06-08 Ethics committee of Tabriz University of Medical Sciences Ethics committeeĜŒ Tabriz University of Medical Sciences, Golgasht Street, Azadi Street, Tabriz Tabriz Iran (Islamic Republic of)