]>
IRCT20131118015446N13 IRCT 2018-02-17 Ahvaz Jundishapur University Of Medical Science Effect Of Glucagon on Treatment Of Acute Severe Asthma Attack Evaluation Of Clinical And Peak Flow Metric Effect Of Intravenous Glucagon On Treatment Of Acute Severe Asthma Attack 2017-10-23 anticipated 20 Complete https://irct.ir/trial/14713 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Table of random numbers, Blinding description: The patients know they are participating in a study that is aimed to evaluate the effect of glucagon on the treatment of severe asthma attack but they are not informed that they receive placebo or glucagon The physician who evaluates the clinical status of patients and the nurse who injects the drug are not aware of the medication that patients receive. 3 Asthma. Intervention 1: Intravenous injection of 1 mg of glucagon over 1minute for case group. Intervention 2: Intravenous injection of 1 mL normal saline for control group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is We will make a decision about sharing all needed data very soon.
public Dr Hassan Motamed
Department of emergency medicine, Golestan Hospital, Farvardin Street, Ahvaz,Iran
Ahvaz Iran (Islamic Republic of) 61357-33118 +98 61 3374 3099 motamed-h@ajums.ac.ir Ahvaz Jundishapur University Of Medical Science scientific Dr Hassan Motamed
Department of emergency medicine, Golestan Hospital, Farvardin Street, Ahvaz, Iran
Ahvaz Iran (Islamic Republic of) 61357-33118 +98 61 3374 3099 motamed-h@ajums.ac.ir Ahvaz Jundishapur University Of Medical Science Iran (Islamic Republic of) Iran (Islamic Republic of) Severe asthma attack Age between 18 and 55 18 years 55 years Both History of diabetes mellitus Smoking Ischemic heart disease Emphysema or chronic bronchitis Insulinoma pheochromocytoma Current oral or injectable corticosteroids, pregnancy Pregnancy Lactation Need for intubation J45 Asthma Treatment - Drugs Treatment - Drugs Intravenous injection of 1 mg of glucagon over 1minute for case group Intravenous injection of 1 mL normal saline for control group Peak Expiratory Flow Rate (PEFR). Timepoint: At 0, 10, 15, 30, 45 ,60 minutes after intervention. Method of measurement: Litre/minute, by spirometry. FEV1. Timepoint: At 0, 10, 15, 30, 45 ,60 minutes after intervention. Method of measurement: Litre, by spirometry. Respiratory rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of respiration in one minute. Pulse rate. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Counting of pulse in one minute. Blood pressure. Timepoint: At 0 and 60 minutes after intervention. Method of measurement: mmHg, by sphygmomanometer. Blood glucose. Timepoint: At 0 and 20 minutes after intervention. Method of measurement: mg/dL, by glucometer. Blood oxygen saturation levels (SpO2). Timepoint: At 0 and 60 minutes after intervention. Method of measurement: Percentage, by pulse oximeter. Ahvaz Jundishapur University Of Medical Science Approved 2017-09-26 Ethics committee of Ahvaz Jundishapur University of Medical Science Ahvaz Jundishapur University Of Medical Science, Golestan Highway, Ahvaz Ahvaz Khouzestan Iran (Islamic Republic of)