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IRCT2013120815706N1 IRCT 2014-01-28 Deputy of resaerch Comparison antipyretic effect of Acetaminophen and Ibuprofen alone and together Comparison antipyretic effect of Acetaminophen and Ibuprofen alone and together infant and children between 6 month and 10 years of age 2013-03-21 anticipated 540 Complete https://irct.ir/trial/14895 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 Fever. Intervention 1: Temperature of fever at the start for each group is considered as a control. It should be noted that all three groups before the intervention were similar in all respects. Then the group A we took acetaminophen of 120mg/5ml with dose 15 mg per kg of body weight every six hours for 24 hours. Intervention 2: In group B, ibuprofen of 100mg/5ml with dose of 10 mg per kg every six hours for 24 hours. Intervention 3: and in Group C acetaminophen dose of 15 mg per kg of body weight and ibuprofen at a dose of 10 mg per kg of body weight the body was given every six hours for 24 hours. Therefore, control considered at the time of entrance and intervention considered after entrance.
public Dr Noor Mohammad Noori
Zahedan University of Medical Sciences, Imam Ali Hospital
Zahedan Iran (Islamic Republic of) +98 54 1342 5611 dr_noori_cardio@yahoo.com Zahedan University of Medical Sciences scientific Dr Noor Mohammad Noori
Imam Ali Hospital
Zahedan Iran (Islamic Republic of) +98 54 1342 5611 dr_noori_cardio@yahoo.com Zahedan University of Medical Sciences Iran (Islamic Republic of) From all feverish children between 6 months to 10 years who presented to the emergency center for children of Ali ibn Abi Talib Hospital, those considered for study with fever above 38 as inclusion criteria. Children who need hospitalization, they are clinically dehydrated; history of intolerance, allergies and contraindications or drug use have chronic lung disease except asthma , cardiac, neurologic , hepatic and renal have and their parents ability to care for children at home may not be excluded. no limit 10 years Both R50.9 Fever, unspecified Treatment - Drugs Treatment - Drugs Treatment - Drugs Temperature of fever at the start for each group is considered as a control. It should be noted that all three groups before the intervention were similar in all respects. Then the group A we took acetaminophen of 120mg/5ml with dose 15 mg per kg of body weight every six hours for 24 hours. In group B, ibuprofen of 100mg/5ml with dose of 10 mg per kg every six hours for 24 hours. and in Group C acetaminophen dose of 15 mg per kg of body weight and ibuprofen at a dose of 10 mg per kg of body weight the body was given every six hours for 24 hours. Therefore, control considered at the time of entrance and intervention considered after entrance. Fever. Timepoint: 2, 4, 6 hours after consumption. Method of measurement: Using axillary thermometer method. Deputy of resaerch Approved 2012-09-27 Zahedan University of Medical Sciences (ZaYMS) Dr Hesabi Circle, ZaYMS Pardis Zahedan Iran (Islamic Republic of)