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IRCT2014011316209N1 IRCT 2015-05-20 Vice chancellor for research, Shiraz University of Medical Sciences Aerobic exercise in cardiovascular disease The influence of aerobic exercise on serum Brain Natriuretic Peptide and C- Reactive Protein in cardiovascular disease 2013-07-21 anticipated 60 Complete https://irct.ir/trial/15241 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Cardiovascular. Intervention 1: Aerobic exercise instruments: ergo meter bicycle 60-55% of their target heart rate 3 sessions per week. Intervention 2: In this group, no intervention is done.
public Najmeh Sheykhiyan
Shiraz University of Medical Science, Zand street, Shiraz, Fars, Iran
Shiraz Iran (Islamic Republic of) +98 71 3235 7282 ysheykheyan.mh@gmail.com; ostovanm@gmail.com Shiraz University of Medical Science scientific Mohammadali Ostovan
Cardiac Department, Namazi Square, Zand street, Shiraz, Fars, Iran
Shiraz Iran (Islamic Republic of) 71937-11351 +98 71 3626 2011 ostovanm@gmail.com Shiraz University of Medical Science Iran (Islamic Republic of) Inclusion criteria:In this trial patients with coronary artery disease more than 70 percent at least in one coronary vessel with Ejection Fraction more than 40 percent in recent Echo cardiograph without acute evidence of ischemia or congestive heart failure symptoms were selected and are divide randomly into two groups. exclusion criteria:patients with acute evidence of ischemia or congestive heart failure symptoms are excluded. 40 years 65 years Both I51.6 Disease, diseased - cardiovascular Prevention N/A Aerobic exercise instruments: ergo meter bicycle 60-55% of their target heart rate 3 sessions per week In this group, no intervention is done. Brain Natriuretic Peptide. Timepoint: Before intervention and 2 months after intervention. Method of measurement: ELISA. C- Reactive Protein. Timepoint: Before intervention and 2 months after intervention. Method of measurement: ELISA. Heart rate. Timepoint: At the beginning and at the end of 8 weeks. Method of measurement: Electrocardiogram. Blood pressure. Timepoint: At the beginning and at the end of 8 weeks. Method of measurement: Sphygmomanometer. Vice chancellor for research, Shiraz University of Medical Sciences Approved 2014-01-04 Ethics committee of Shiraz University of Medical Sciences Shiraz University of Medical Science, Zand street, Shiraz, Fars, Iran Shiraz Iran (Islamic Republic of)