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IRCT138803311946N3 IRCT 2010-12-08 Vice Chancellor for research, Guilan University of Medical Sciences The effect of Isosorbide Mononitrate on induction success The effect of Isosorbide Mononitrate (vs. placebo) on induction success in pregnant women 2009-08-27 anticipated 72 Complete https://irct.ir/trial/1527 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. 2 Other assisted single delivery. Intervention 1: Isosorbide Mononitrate, 40mg, vaginal for the caces. Intervention 2: Placebo for the control group.
public Mandana Mansuor Ghanaie
Reproduction Health research center, Alzahra hospital, Namjo street
Rasht Iran (Islamic Republic of) +98 13 1322 5624 m_m_ghanie@gums.ac.ir Guilan University of Medical Sciences scientific Mandana Mansur Ghanaie
Reproduction Health research center, Alzahra hospital, Namjo street
Rasht Iran (Islamic Republic of) +98 911 331 3240 m_m_ghanaie@gums.ac.ir Guilan University of Medical Sciences Iran (Islamic Republic of) The inclusion criteria: 1-single pregnancy, 2- cephalic presentation, 3- Bishop Score ≤6, 4-normal AFI>5, 5- regular FHR, 6- intact membrane, 7- gestational age ≥37 weeks. Exclusion criteria are: Uterine contraction (≥3 contraction 45’’ in 10 minutes) previous mymomectomy, history of headache, intolerance IMN, cardiopulmonary disease, vaso previa or placenta previa, cord prolepses, classic incision or previous myomectomy, irregular FHR, multiple pregnancy, macrosomia, polyhydramious, severe preeclampsia, maternal short stature. 15 years 45 years Female O83 Other assisted single delivery Treatment - Drugs Placebo Isosorbide Mononitrate, 40mg, vaginal for the caces Placebo for the control group Labor course. Timepoint: Hospitalization to delivery. Method of measurement: Based on Documented data. Delivery mode. Timepoint: Post partum. Method of measurement: Based on Documented data. Bleeding volume in labor and post partum. Timepoint: Control of labor course. Method of measurement: Based on Documented data. Hospitalization duration and active phase initiation. Timepoint: Control of labor course. Method of measurement: Based on Documented data. Newborn apgar score. Timepoint: Immediately after delivery. Method of measurement: Based on documented data. NICU requirement. Timepoint: Post partum. Method of measurement: Based on documented data. The rate of maternal palpitation. Timepoint: During labor. Method of measurement: Based on documented data. The occurance of maternal headache. Timepoint: Control during labor & delivery. Method of measurement: Based on documented data. The ocurrance of tachysystol/hypersystol and hyperstimulated syndrome. Timepoint: FHR monitoring during labor. Method of measurement: Based on documented data. Vice Chancellor for research, Guilan University of Medical Sciences Approved Vice chancellor for research, Guilan University of Medical Sciences Opposite of Azodi Studium, Namjo street Rasht Iran (Islamic Republic of)