IRCT2014012216309N1 IRCT 2014-04-18 Vice-chancellor for Research of Sabzevar University of Medical Sciences Comparison the effect of chlorhexidine solution and toothbrush in the prevention of oral lesions The comparison between chlorhexidine solution and toothbrush in prevention of oral lesions in patients hospitalized in intensive care unit 2013-11-15 anticipated 30 Complete https://irct.ir/trial/15298 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: In this double blind randomized clinical trial samples in the two groups will be labeled by letters A, B and The researcher who measures the Implications of the study is unaware of the intervention groups. Patients are also blind as they are unconscious at the time of intervention. N/A Condition 1: Gingivitis. Condition 2: Other diseases of lip and oral mucosa. Condition 3: Diseases of tongue. Intervention 1: Intervention group: After approving of the study by sciences vice chancellor of Sabzevar University of medical sciences and completing the written consent forms by all participants in the study, Patients are divided randomly into two equal groups: 15 patients in intervention and 15 in control group. In the intervention group, internal and external surfaces of the teeth and gums are rotationally brushed by using a soft kid's toothbrush and half a centimeter toothpaste .This action is done every 8 hours during 4 days. Intervention 2: Control group: control group members wash their mouth with 0.2 %( zero point two percent) chlorhexidine solution. This action is also done every 8 hours for 2 minutes during 4 days but for control group. Also, the observation of mouth is done by BOAS and MPS every 8 hours before utilizing a mouthwash (before washing mouth by chlorhexidine solution). Then, we record it in a checklist.