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IRCT2015092716516N2 IRCT 2015-11-25 Vice Chancellor for research of lorestan University of Medical Sciences The Comparison of inhaled and intravenous anesthesia on depth of anesthesia and hemodynamic changing in Cholecystectomy Laparoscopic. The Comparison of inhaled and intravenous anesthesia on depth of anesthesia and hemodynamic changing in Cholecystectomy Laparoscopic. 2015-10-07 anticipated 92 Complete https://irct.ir/trial/15432 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Other design features: Method randomization: block Randomized. N/A General anesthesia. Intervention 1: Intervention group 1: In the operating room patients catheterized and intravenous fluids injected .Prodrug is contains 2 ml narcotic sufentanil and 2 mg midazolam.Induction of anesthesia is done by sodium thiopental and atracurium, Then intubation is performed,In this group (Group T), maintenance of anesthesia perform with propofol 100 mg per kg of body weight per minute. Manufacturer: pharmaceutical company of dongkook, Manufactured by country of Korea. Intervention 2: Control group: In the operating room patients catheterized and intravenous fluids injected .Prodrug is contains 2 ml narcotic sufentanil and 2 mg midazolam.Induction of anesthesia is done by sodium thiopental and atracurium, Then intubation is performed,In this group (Group v), maintenance of anesthesia perform withwith Sevoflurane 1.2%. Manufacturer: pharmaceutical company of BAXTER, Manufactured by country of GUAYAMA.
public Farzad Mohammadi
Lorestan, Khorramabad, Lorestan University of Medical Sciences Research Department
Khorramabad Iran (Islamic Republic of) 381251698 +98 66 3322 3004 farzad871410053@yahoo.com Deputy of Research, Lorestan University of Medical Sciences scientific S. Nadri doctor
Lorestan, Khorramabad, Lorestan Medical Sciences University Research Assistant
Khorramabad Iran (Islamic Republic of) 381251698 +98 66 3322 3004 dr.s.nadri@gmail.com Deputy of Research, Lorestan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria:All patients 20 to 40 years undergoing laparoscopic cholecystectomy referred to Shohada hospital in Khorramabad in the second half of 1394. Exclusion criteria:Lack of consent to participate in research projects, heart problems, allergies to eggs, a history of sensitivity to anesthesia, conversion laparoscopic surgery to open surgery, cholecystectomy, high blood pressure, history of diabetes. 20 years 40 years Both K80-K87 Disorders of gallbladder, biliary tract and pancreas Treatment - Surgery Treatment - Surgery Intervention group 1: In the operating room patients catheterized and intravenous fluids injected .Prodrug is contains 2 ml narcotic sufentanil and 2 mg midazolam.Induction of anesthesia is done by sodium thiopental and atracurium, Then intubation is performed,In this group (Group T), maintenance of anesthesia perform with propofol 100 mg per kg of body weight per minute. Manufacturer: pharmaceutical company of dongkook, Manufactured by country of Korea Control group: In the operating room patients catheterized and intravenous fluids injected .Prodrug is contains 2 ml narcotic sufentanil and 2 mg midazolam.Induction of anesthesia is done by sodium thiopental and atracurium, Then intubation is performed,In this group (Group v), maintenance of anesthesia perform withwith Sevoflurane 1.2%. Manufacturer: pharmaceutical company of BAXTER, Manufactured by country of GUAYAMA Blood pressure. Timepoint: Before induction of anesthesia, after premedication injection, after induction of anesthesia, after intubation, during surgery four times, after extubation،And with an interval of every 15 minutes. Method of measurement: Millimeters of mercury using a sphygmomanometer. Heart rate. Timepoint: Before induction of anesthesia, after premedication injection, after induction of anesthesia, after intubation, during surgery four times, after extubation،؛And with an interval of every 15 minutes. Method of measurement: Depending on the number of beats per minute monitoring device. Depth of Anesthesia. Timepoint: Before induction of anesthesia, after premedication injection, after induction of anesthesia, after intubation, during surgery four times, after extubation،And with an interval of every 15 minutes. Method of measurement: Based on the electrical brain waves and by BIS device. Vice Chancellor for research of lorestan University of Medical Sciences Approved 2015-09-22 Ethics Committee of Lorestan University of Medical Sciences Lorestan،Khorramabad،Lorestan University of Medical Sciences Khorramabad Iran (Islamic Republic of)