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IRCT2014042017360N1 IRCT 2014-10-03 Ahvaz jundishapour university of medical science The effect of levodopa on stroke MCA,BI,RMI,CVA. The comparision between levodopa effect and placebo on the improvement of motor function in the patients with stroke in MCA(Middle cerebral artery),randomized.double blind study. 2013-04-04 anticipated 114 Complete https://irct.ir/trial/15980 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Ischemic stroke. Intervention 1: Intervention group: levodopa-c tablet 1oo/25 mg daily for 21 days in the patients with ischemic stroke in MCA territory. Intervention 2: Control group: placebo tablet 125mr daily for 21 days,in the patients with ischemic stroke in MCA territory.
public Dr. Alireza Hasanzade
Neurolology Department, Golestan Hospital, Golestan, Ahvaz
Ahvaz Iran (Islamic Republic of) 6135733118 +98 61 1374 3012 hassanzadehar@gmail.com Ahvaz Jondishapour University of Medical Sciences scientific Dr. Ali Nakhostin Mortazavi
Neurolology Department, Golestan Hospital, Golestan, Ahvaz
Ahvaz Iran (Islamic Republic of) 6135733118 +98 61 1374 3012 anmortazavi@yahoo.com Ahvaz Jondishapour University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: the patients with ischemic strroke in the MCA territory. Exclusion criteria: 1.major depression, 2.cardiovascular disease 3.tricyclic therapy 4.SSRI therapy 5.dementia. no limit no limit Both G46* Middle cerebral artery syndrome (I66.0+) Treatment - Drugs Placebo Intervention group: levodopa-c tablet 1oo/25 mg daily for 21 days in the patients with ischemic stroke in MCA territory. Control group: placebo tablet 125mr daily for 21 days,in the patients with ischemic stroke in MCA territory. Motor function. Timepoint: three weeks after treatment. Method of measurement: Rivermead mobility index and Barthel index. Language recovery. Timepoint: 4 weeks after treatment. Method of measurement: NIHSSSا. Comparision between motor recovery of upper and lower limbs. Timepoint: 3 weeks after treatment. Method of measurement: Rivermead mobility index and Barthel index. Spastisity. Timepoint: 3 months after treatment. Method of measurement: Ashworth modified scale. Ahvaz jundishapour university of medical science Approved 2013-04-05 Ahvaz jundishapour university of medical science Central Building, University City, Golestan,Ahvaz ahvaz Iran (Islamic Republic of)