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IRCT2017061317756N18 IRCT 2017-07-10 Vice-Chancellery of Research and Technology at Birjand University of Medical Sciences Eradication of helicobacter Pylori in triple therapy regimen supplemented by green tea extract compared with routine triple therapy regimen A clinical trial on the effects of green tea extract plus triple therapy regimen compared with triple therapy regimen on eradication of helicobacter Pylori in in patients diagnosed with helicobacter Pylori infection 2016-03-20 anticipated 60 Complete https://irct.ir/trial/16258 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 Helicobacter pylori. Intervention 1: Intervention Group: The intervention group received the routine triple therapy regimen plus green tea extract pill (450 mg twice daily) for two weeks. Four weeks after completion of intervention, urease breath test was performed. Intervention 2: Control Group: The control group only received the routine triple therapy regimen for two weeks. Four weeks after completion of intervention, urease breath test was performed.
public Laila Omidvar
Faculty of Medicine, Birjand University of Medical Sciences, Ghaffari St.,
Birjand, Iran (Islamic Republic of) +98 56 3239 5680 Roozgar@bums.ac.ir Birjand University of Medical Sciences scientific Laila Omidvar
Faculty of Medicine, Birjand University of Medical Sciecnes, Ghaffari St.,
Birjand, Iran (Islamic Republic of) +98 56 3239 5680 roozgar@bums.ac.ir Birjand University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Positive result of urease breath test (UBT) and/or rapid urease test for diagnosis of helicobacter pylori; having indications for Helicobacter pylori treatment; willingness to cooperate in the study; lack of green tea consumption by the patient prior to the study onset; no history of macrolide. Exclusion criteria: Previous treatment for helicobacter pylori; consumption of proton pump inhibitors from a month before the test, or blockers of H2 receptor 24 hours before the test, or antibiotics and bismuth from two weeks before the test; pregnancy; malignancy; gastrectomy; severe liver disease or any other severe disease within the past two years; any sensitivity to penicillin or other substances used in the medication regimen; incomplete consumption of the drugs for any reason. no limit no limit Both B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters Treatment - Drugs Treatment - Drugs Intervention Group: The intervention group received the routine triple therapy regimen plus green tea extract pill (450 mg twice daily) for two weeks. Four weeks after completion of intervention, urease breath test was performed. Control Group: The control group only received the routine triple therapy regimen for two weeks. Four weeks after completion of intervention, urease breath test was performed. Eradication of helicobacter pylori. Timepoint: Four weeks after intervention was completed. Method of measurement: Urease breath test. Vice-Chancellery of Research and Technology at Birjand University of Medical Sciences Approved 2016-03-08 Ethics Committee of Birjand University of Medical Sciences Vice-chancellery of Research and Technology, Birjand University of Medical Sciences, Ghaffari St., Birjand, Iran (Islamic Republic of)