]>
IRCT2014100617891N4 IRCT 2014-12-09 Vice Chancellor for Research evaluation the effect of erythropoitin on multiple trauma patients that need blood transfusion evaluation the effect of recombinant erythropiotin on Haft -e- Tir & Sina hospitals' multiple trauma patients' need to recurrrent blood transfusion & noninvasive hemodynamic & laboratory parameters 2014-12-06 anticipated 60 Complete https://irct.ir/trial/16358 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive. N/A blood transfusion in multiple trauma patient. Intervention 1: Intra venous transfusion of recombinant erythropoitin as 300 unit per Kg of patiant's weight in two minutes duration slowly under cardiac & respiratory monitoring in intervention group as a single dose together with blood transfusion in first day of hospital admission of patiant in hospital. Intervention 2: would not be done in control group.
public Ali Mannani
Shohadaye Haftom -e- Tir hospital , Emergency ward
Tehran Iran (Islamic Republic of) 1886718136 +98 21 6653 3686 alimannani@yahoo.com Iran University of Medical Science scientific Nader Tavakoli
Sattar khan Avenue , Niayesh street , Hazrate rasool hospital
Tehran Iran (Islamic Republic of) 14455-364 +98 21 6651 7341 tavakoli.n@iums.ac.ir Iran University of Medical Science Iran (Islamic Republic of) Iran (Islamic Republic of) inclusion criteria:being Multiple Trauma, age more than18 years, blood transfusion within 24 hours of enterance to the hospital, consiouss agreement of the patient (if has ability to decide & is completely alert) or his legal attendant/ deputy(in other situations),no affection to other diseases exclusion criteria: consiouss disagreement of the patient or his legal attendant/ deputy during the research,death of patient within first three days of hospital admission 18 years no limit Both T79.2 Traumatic secondary and recurrent haemorrhage Treatment - Drugs N/A Intra venous transfusion of recombinant erythropoitin as 300 unit per Kg of patiant's weight in two minutes duration slowly under cardiac & respiratory monitoring in intervention group as a single dose together with blood transfusion in first day of hospital admission of patiant in hospital would not be done in control group Blood transfusion volume to the patient. Timepoint: end of patient admission at the hospital. Method of measurement: number of pack cells with counting the documented transfused pack cells in patients' files. Blood pressure. Timepoint: at the begining & third day of trial. Method of measurement: mm Hg with using mercury sphingomanometer set. Heart beats. Timepoint: at the begining & third day of trial. Method of measurement: number of heart beats per minute with using heart monitoring set. Blood oxygen saturation. Timepoint: at the begining & third day of trial. Method of measurement: percent of blood oxygen saturation with using pulse oximeter set. Respiratory rate. Timepoint: at the begining & third day of trial. Method of measurement: number of patient's breath per minute with physical examination. Plasma hepcidin. Timepoint: third day of trial. Method of measurement: nanogram per mililiter with using elisa technique. Urine microalbumine to creatinine ratio. Timepoint: third day of trial. Method of measurement: miligram on milimoll with using radiimmunoassay & Jaffe techniques respectively. Stay lenghth of patient in hospital. Timepoint: end of patient's admission in hospital. Method of measurement: number of admission days of patient in hospital with using formula discharge date minus admission date plus one. Patiant's hotelling price in hospital. Timepoint: end of patient's admission in hospital. Method of measurement: price documented in patiant's echonomic file in Rials. Vice Chancellor for Research Approved 2014-09-28 vice chanceller for research of Tehran medical science university Keshavarz Boulevard corner of Ghods bystreet central organization of Tehran medical science university 6th floor Tehran Iran (Islamic Republic of)