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IRCT2014061518099N1 IRCT 2016-05-26 Deputy Of Research And Technology, Shahrekord ,Medical Sciences University Of The effect of Methocarbamol on preventing of muscle fasciculation Comparison of the effect of Atracurium and Methocarbamol on preventing of muscle fasciculation induced by Succinylcholine 2012-03-24 anticipated 58 Complete https://irct.ir/trial/16508 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Patients and researchers investigating fasciculation are unaware of the group assigning. 3 The relation between the effect of Methocarbamoland neuromuscular in preventing of fasciculation induced by succinylcholine. Intervention 1: Fifty-eight adults ASA I or II patients whom were hospitalized for elective surgery were randomly assigned in to two groups: group "A" (n= 29) whom were received succinylcholine 1 mg/kg body weight intravenously followed by methocarbamol 1g. and patients in group "B" (n= 29) whom were received succinylcholine 1 mg/kg body weight intravenously followed by 0.1 effective dose of atracorium . Anesthesia was induced in all patients with thiopental sodium 3-5 mg/kg . Intervention 2: In the first group before succinylcholine one mg kg Methocarbamol was given intravenously in all patients. Anesthetic thiopental in the three to five milligrams per kg was done for all patients. Intervention 3: In the second group before succinylcholine one mg kg of atracurium (as much as one-tenth the dose of the drug relaxant) was used intravenously. Anesthesia was induced in all patients with intravenous injection of sodium thiopental at a dose of three to five mg kg .
public Mahmoud Mobasheri
Kashani Blvd, Shahrekord, Medical Sciences University Of
Shahrekord Iran (Islamic Republic of) 8815712471 +98 38 1333 0061 pajoohesh@skums.ac.ir Shahrekord University Of Medical Sciences scientific Gholamreza Shabanian
Ayatollah Kashani Hospital, Parastar Street
Shahrekord Iran (Islamic Republic of) 8815712471 +98 22 20016 gshabanian@skums.ac.ir Shahrekord University Of Medical Sciences Iran (Islamic Republic of) Inclusion criteria : ASA physical status I and II; not be addicted to opiate; age between 18 to 60 years. Exclusion criteria : spinal injuries; hepatic or renal failure; cardiac ischemia; pulmonary; metabolic diseases and pregnancy 17 years 59 years Both Prevention Treatment - Drugs Treatment - Drugs Fifty-eight adults ASA I or II patients whom were hospitalized for elective surgery were randomly assigned in to two groups: group "A" (n= 29) whom were received succinylcholine 1 mg/kg body weight intravenously followed by methocarbamol 1g. and patients in group "B" (n= 29) whom were received succinylcholine 1 mg/kg body weight intravenously followed by 0.1 effective dose of atracorium . Anesthesia was induced in all patients with thiopental sodium 3-5 mg/kg . In the first group before succinylcholine one mg kg Methocarbamol was given intravenously in all patients. Anesthetic thiopental in the three to five milligrams per kg was done for all patients. In the second group before succinylcholine one mg kg of atracurium (as much as one-tenth the dose of the drug relaxant) was used intravenously. Anesthesia was induced in all patients with intravenous injection of sodium thiopental at a dose of three to five mg kg . Muscle fasciculation. Timepoint: right after injection of succinylcholine. Method of measurement: (0-4 score system) scale. observational. Deputy Of Research And Technology, Shahrekord ,Medical Sciences University Of Approved 2010-08-15 Shahrekord University Of Medical Sciences Kashani Blvd, Shahrekord, Medical Sciences University Of Shahrekord Iran (Islamic Republic of)