IRCT2014111318342N3 IRCT 2015-01-10 Vice chancellor for research, Qazvin University of Medical Sciences Assessment the effect of body position during sleep on the pressure of the respiratory tract in brain injury patients Assessment the effect of changing body position on endotracheal tube cuff pressure in head trauma patients with mechanical ventilation who admitted in ICU ward 2014-10-27 anticipated 30 Complete https://irct.ir/trial/16660 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention. N/A Head trauma. First the patients will be placed in a neutral position (° angle to the head of the bed and head towards the body) for initiating data collection. Tracheal tube cuff pressure in end-expiratory pause (for 4-5 seconds) of mechanical ventilation can be measured and recorded in cm water with a standard manometer, If the cuff pressure is in inappropriate level, endotracheal tube cuff pressure will adjust in the range of 27 cm H2o. Then the patient's position will change in each two hours sequence determined by researcher; left lateral position with a 30° angle to the head of the bed and head towards the body, right lateral position with a 30° angle to the head of the bed and head towards the body, semi-upright position at 45° angle to the head of the bed and head towards the body, left lateral position with 45° angle to the head of the bed and head towards the body, right lateral position with a 45° angle to the head of the bed and head towards the body. In each patient's change position, endotracheal tube cuff pressure will measure and record immediately before and after change position, after 15 minutes and finally after 2 hours. Patient's body core temperature, blood pressure, respiratory rate and heart rate will measure before and after change position, after 15 minutes and finally after 2 hours using infrared thermometer and monitoring devices. Patients during the measurements should be at level 5 according to the Richmond Agitation Sedation Scale and based on behavioral pain scale , they should be at 3-4 level, otherwise they will be excluded..