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IRCT2014072018536N1 IRCT 2017-03-21 Dr Radmanesh clinic Evaluation of PDL laser for the treatment of cutaneous leishmaniasis Clinical trial for the Comparison of the effect of PDL laser and injection of glucantime in the treatment of cutaneous lesions of leshmaniasis patients 2017-01-04 anticipated 38 Complete https://irct.ir/trial/16779 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Cutaneous leishmaniasis. Intervention 1: Intervention group 1: For one of the lesions, glucantime (vial 1gr/5cc) will be injected intralesional with insulin syringe. The interval between the injections will be one week until the lesion will be completely cured and maximum 10 injections will be done. Intervention 2: Intervention group 2: The other lesion will be treated with PDL laser(N light, model A00-0159) with the setting of 7j/cm2 fluence, and 5cm spot size. Laser therapy will be continued with 2 weeks interval, until complete cure of the lesion or maximum 4 sessions.
public Ehsan Omidian
Imam khomeini hospital, Azadegan st, Ahvaz
Ahvaz Iran (Islamic Republic of) +98 33302058 Omidian.e@ajums.ac.ir Ahvaz Jondishapur University of Medical Sciences scientific Seyed Mohammad Radmanesh
Imam khomeini hospital, Azadegan st, Ahvaz
Ahvaz Iran (Islamic Republic of) +98 61 3336 2054 radmanesh.m@ajums.ac.ir Ahvaz jondishapour university Iran (Islamic Republic of) Inclusion criteria: Age between 5-55 years; having at least 2 leishmania lesion on the everywhere of body skin with positive direct smear for leishman body. Exclusion criteria: Pregnancy; lactation; using any other treatments before the beginning of the study. 5 years 55 years Both B55.1 Cutaneous leishmaniasis Treatment - Drugs Treatment - Devices Intervention group 1: For one of the lesions, glucantime (vial 1gr/5cc) will be injected intralesional with insulin syringe. The interval between the injections will be one week until the lesion will be completely cured and maximum 10 injections will be done. Intervention group 2: The other lesion will be treated with PDL laser(N light, model A00-0159) with the setting of 7j/cm2 fluence, and 5cm spot size. Laser therapy will be continued with 2 weeks interval, until complete cure of the lesion or maximum 4 sessions. Induration index. Timepoint: Before the begionning of the study, Every 2 weeks for 10 weeks. Method of measurement: Physical examination by dermatologist. Post inflammatory hyperpigmantation. Timepoint: Every 2 weeks for 10 weeks. Method of measurement: Physical examination by dermatologist. Dr Radmanesh clinic Approved 2014-04-23 Ethics committee of Ahvaz Jondishapur University of Medical Sciences Daneshgah sq, Ahvaz, Iran Ahvaz Iran (Islamic Republic of)