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IRCT2014080518694N1 IRCT 2014-10-28 Vice chancellor for research, Arak University of Medical Sciences Effects of Echinacea on Ventilator – Associated Pneumonia Comparsion the effects of Echinacea and normalsaline mouthwashes on Ventilator Associated Pneumonia in intubated patients in intensive care units. Arak 2014-06-22 anticipated 70 Complete https://irct.ir/trial/16877 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. 2 Ventilator Associated Pneumonia. Intervention 1: Intervention group: Echinacea mouthwash 1%, 30cc,two times a day using a toothbrush for fifth days. Intervention 2: Control group: normal saline mouthwash using a toothbrush, 30cc,two times a day using a toothbrush for fifth days. http://www.ijmsn.ir Abstract<br /> <br /> Introduction: Ventilator associated pneumonia (VAP) is a problem threatening patients in Intensive Care Units and has a high prevalence. Mouthwash is a caring procedure which can decrease the rate of VAP. The present study aims to compare the effects of Echinacea and normal saline mouthwash on ventilator associated pneumonia prevalence.<br /> Material and Methods: This is a clinical trial in which 70 intubated patients in intensive care units of educational hospitals in Arak city, were selected purposively and allocated in two intervention (Echinacea mouthwash) and control (normal saline mouthwash) groups randomly. VAP was diagnosed by completing Clinical Pulmonary Infection Scale (CPIS), before and at fifth day of the intervention. The rate of ventilator associated pneumonia was compared in the two groups. Data was analyzed using Chi square and t tests.<br /> Results: The two groups were not significantly different regarding demographic characteristics. Ventilator associated pneumonia prevalence was 60% in normal saline and 51.4% in Echinacea group. There was no significant difference between the two groups.<br /> Conclusion: Despite the lower rate of VAP in intervention group, results showed that this difference was not significant.<br /> <br /> Keywords: Intensive care, mouthwash, Echinacea, normal saline, Ventilator associated pneumonia<br /> <br />
public Maryam Gholami Mehrabadi
Valiasr hospital; Valiasr street;Arak;Iran
Arak Iran (Islamic Republic of) 3813645919 +98 86 3223 1169 m.gholami@arakmu.ac.ir; m.mehrabadi.gholami@gmail.com. Arak University of Medical Sciences scientific Sharareh Khosravi
Nursing and Midwifery Faculty, Arak University of Medical;Sardasht street;;Arak;Iran
Arak Iran (Islamic Republic of) 3848176941 +98 86 3417 3502 khosravi@arakmu.ac.ir; Shararehkh2011@yahoo.com Arak University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: having a tracheal tube; aged 18-65 years; less than 12 hours of hospitalization in the intensive care unit before. Exclusion criteria: patients transferred from the intensive care unit; patients died before completion of the study; any damage caused by endotracheal intubation; airway or any other physical cause; antibiotic use before admission; admission in other units before intensive care unit; pregnancy; history of allergy to herbal substances; chronic diseases of immune system. 18 years 65 years Both J17.0 Pneumonia in diseases classified elsewhere Treatment - Drugs Treatment - Drugs Intervention group: Echinacea mouthwash 1%, 30cc,two times a day using a toothbrush for fifth days Control group: normal saline mouthwash using a toothbrush, 30cc,two times a day using a toothbrush for fifth days Ventilator Associated Pneumonia. Timepoint: Before intervention and in the fifth day of intervention. Method of measurement: Clinical Pulmonary Infection Score (CPIS). Vice chancellor for research, Arak University of Medical Sciences Approved 2014-05-21 Ethics Committee Arak University of Medical Sciences Arak University of Medical Scienes;Sardasht; street;Arak;Iran Arak Iran (Islamic Republic of)