]>
IRCT2014082618939N1 IRCT 2014-10-06 Vice chancellor for research, Kermanshah University of Medical Sciences probing effect in contaminated surgical wounds A survey of wound probing effectiveness on surgical site infection in patients with perforated appendicitis 2014-10-07 anticipated 114 Complete https://irct.ir/trial/17052 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention, Other design features: In this survey, after obtaining informed consent and based on inclusion and exclusion criteria, patients are entered in study. A number is granted to each patient in order of entering to study; (from 1 to 114). To randomization, odd numbers are placed in the intervention group and even numbers in the control group. N/A Perforated acute appendicitis. Intervention 1: Just a simple dressing is done daily. Intervention 2: Surgical wound probing is done only once a day during hospitalization until the wound is impenetrable. Probing is done with a cotton-tipped, sterile dry swab between stitches to depth of external oblique fascia. Simple dressing is applied after wound probing. Swabs are purchased from Bistoon-Teb company and become sterile in Imam Reza Hospital. Cotton-tipped swab contains no antiseptic or antibiotics. Background: While advances have been made in infection control practices, including prophylactic and sterile methods, surgical site infections remain a substantial cause of morbidity, prolonged hospitalization, and death. But in the age of antibiotic resistance and in order of preventing wound infection, various local methods have been devised. Wound probing is one of them that needs for more investigations.<br /> Material and methods: A total of 114 patients with perforated appendicitis were included in this single blind clinical trial. All of them were given standardized preoperative antibiotic and underwent appendectomy through Mc-burney incision with primary closure. They were randomized into two equal groups of control (A) and wound probing (B). In control group we only used simple daily dressing and in probing group we used a cotton-tipped swab for probing between stitches every morning. Our follow-up for assessing wound infection was at 1 week and 3 weeks after discharge.<br /> Results: Of the 114 patients enrolled in this study, there were eleven (9.6%) wound infection (seven in group A and four in group B). In the base of our survey, although the patients in probing group had a lower wound infection (7%) in comparison with control group (12.3%), but statistic analysis did not demonstrate any significant difference (p > 0.05). Hospitalization length and charge, and wound healing were similar between two groups.<br /> Conclusion: Use of surgical wound probing in patients underwent appendectomy for perforated appendicitis has no significant effect in preventing wound infection. <br /> Keywords: Wound infection, Prophylaxis, Perforated appendicitis, Primary closure, Wound healing<br />
public Amir Hosein Parniaei
Imam Reza Hospital, Parastar Blvd.
Kermanshah Iran (Islamic Republic of) +98 83 3427 6309 amirparnia@gmil.com; ah.parniaee@kums.ac.ir; dr.makhsosy@kums.ac.ir Kermanshah University of Medical Sciences scientific Behnam Reza Makhsousi
General surgery service, Imam Reza Hospital, Parastar Blvd.
Kermanshah Iran (Islamic Republic of) +98 83 3427 6309 dr.makhsosy@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: 1.Ages between 12-60 years old; 2.Operation via Mc-Burney incision due to acute appendicitis; 3.Evidences of perforated appendicitis e.g., a hole, fecalith, abscess or puss observed by surgeon. Exclusion criteria: 1.Non perforated appendicitis; 2.Incision other than Mc-Burney; 3.Pregnancy; 4.Ages less than 12 years old and more than 60 years old; 5.Severe sepsis and Immunodeficiency, diabetes, cardiovascular or renal or respiratory or hepatic insufficiency; 6.Body mass index higher than 30. 12 years 60 years Both K35.0 Acute appendicitis with perforation Other Prevention Just a simple dressing is done daily. Surgical wound probing is done only once a day during hospitalization until the wound is impenetrable. Probing is done with a cotton-tipped, sterile dry swab between stitches to depth of external oblique fascia. Simple dressing is applied after wound probing. Swabs are purchased from Bistoon-Teb company and become sterile in Imam Reza Hospital. Cotton-tipped swab contains no antiseptic or antibiotics. Wound infection. Timepoint: Daily during hospitalization, one week and three weeks after discharge. Method of measurement: Based on clinical examination. Hospitalization time period. Timepoint: At the time of discharge. Method of measurement: Calculating days of hospitalization. Wound healing. Timepoint: Three weeks after discharge. Method of measurement: Based on clinical examination. Vice chancellor for research, Kermanshah University of Medical Sciences Approved 2014-06-07 Ethics committee of Kermanshah University of Medical Sciences Vice Chancellor for Research, Building No.2, Shahid Beheshty Blvd. Kermanshah Iran (Islamic Republic of)