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IRCT2014100719432N1 IRCT 2015-05-31 Tehran University of Medical Sciences Efficacy assessment of cell therapy in skin aging Efficacy assessment of adipose drive stem cell in nasolabial fold wrinkles 2014-11-22 anticipated 16 Complete https://irct.ir/trial/17366 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 3 atrophic disorders of skin (aging). 2cc suspension of adipose drive stem cell (SVF) that made from 100 cc abdominal adipose will injected in nasolabial fold and the end, healing rate of nasolabial fold wrinkle will measured..
public Dr. Mohammadamir Amirkhani
Skin & Stemcell Research Center, Maryam aley, South kamraneye, Tehran, Iran
Tehran Iran (Islamic Republic of) +98 21 2220 1710 amirkhani@health.gov.ir Skin & Stem Cell Research Center of Tehran University of Medical sciences scientific Dr. Mohammadali Nilforoushzade
Skin & Stem Cell Research Center, Maryam aley, South kamraneye, Tehran, Iran
Tehran Iran (Islamic Republic of) +98 21 2220 1710 dr_nilforoush@yahoo.com Skin & Stem Cell Research Center of Tehran University of Medical Science Iran (Islamic Republic of) Inclusion criteria: age about 35 to 55 years old; Having no anatomic disorder in face; Wrinkle type between grade 2 to 4; Normal mental health; Having a good cooperation with research team; Exclusion criteria: being smokers or drinkers; any past skin intervention in face; Having many wrinkles on the face; type of 1 or 5 of wrinkle scoring; having a mental disorder; having an obsessed disorder; having any skin disorder; having any major disorder; having a systemic disorder; having an oral disorder; 35 years 55 years Both L90.9 Atrophic disorder of skin, unspecified Other 2cc suspension of adipose drive stem cell (SVF) that made from 100 cc abdominal adipose will injected in nasolabial fold and the end, healing rate of nasolabial fold wrinkle will measured. Quantity of nasolabial fold wrinkle - Extension. Timepoint: 1- 3 - 6 Month after cell therapy. Method of measurement: Biometry with visioface & skin sonography. Quality of nasolabial fold wrinkle - deep. Timepoint: 1 - 3 - 6 Mounth after intervention. Method of measurement: Visio face & skin sono. Color. Timepoint: 1 - 3 - 6 Month after cell therapy. Method of measurement: Biometry with colorimeter. Elastisity. Timepoint: 1 - 3 - 6 Eounth after intervention. Method of measurement: MPA 9. Tehran University of Medical Sciences Approved 2014-09-07 Tehran University of Medical Sciences Tehran University of Medical Sciences, Cross Qods st, Keshavarz Blvd, Tehran, Iran Tehran Iran (Islamic Republic of)