IRCT2014101819564N1 IRCT 2014-12-07 research of Deputy, Tehran of Medical Sciences University Effect aromatherapy on fatigue and quality of life in hemodialysis patients Comparison the effect of aroma Inhalation and essence massage on fatigue and quality of life in hemodialysis patients 2014-05-22 anticipated 96 Complete https://irct.ir/trial/17486 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research. 2 End Stage Renal Disease. Intervention 1: In group I, two drops of lavender essence with sweet orange at a ratio of 1:1 were dropped on a gas. The gas was pinned to the patient’s collar and the patient was asked to breathe normally for 15-20 minutes. This was done three times a week for 8 weeks. Intervention 2: All subjects in the second group were undergone skin testing before massage with aromatic oil to ensure the absence of sensitivity; in case of redness, itching, swelling, and a positive test, the patient was excluded. The subjects in this group were massaged with 5 mL combination of lavender essence with sweet orange at a ratio of 1:1 which was diluted with sweet almond oil to 3%. The massage was performed on toes, feet and ankles as fondling, without hitting and pressure for 10 minutes during dialysis. This was done three times a week for 8 weeks. The patients were also received routine care of the ward. Intervention 3: The third group (control) received only the standard care.