IRCT2014110519818N1 IRCT 2015-01-03 Iran University of Medical Sciences Inflammation in femoral fractures Alterations in serum inflammatory markers in patients under early and late surgery for femoral fractures 2014-12-22 anticipated 38 Complete https://irct.ir/trial/17624 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: simple randomization, Blinding description: double blind , That is not the patient knew which group under the surgery and not see any sick doctor knew when and what time the surgery group. N/A Fracture of shaft of femur. Intervention 1: all patients with fractures of the femur bone that before 24 hours of admission to the emergency room, a common method of surgery are located and The fracture is fixed only by the plate. Intervention 2: all patients with fractures of the femur bone that After 24 hours of admission to the emergency room, a common method of surgery are located and The fracture is fixed only by the plate. https://www.termedia.pl/Evaluation-of-inflammatory-response-in-patients-undergoing-surgical-treatment-for-early-and-delayed-femoral-fractures,19,28559,1,1.html Our findings suggest that serum levels of IL-8 were markedly decreased from 12 h until 48 h postoperatively (p < 0.05). Moreover, the results indicated that serum levels of TNF- were significantly increased in the early hours, but after 48 h a decreasing trend was detected (p < 0.05). Furthermore, serum levels of IL-10, IFN-, and IL-6 were significantly increased from 12 h until 48 h postoperatively (p < 0.05) Yes - There is a plan to make this available What will be shared: Just part of the original data, such as information related to the outcome or the possibility of sharing it When: Access the course start 6 months after printing the results To whom: Just for researchers working in academic and scientific institutions will be available Conditions: Only the fields of data use is possible Where to obtain: Dr. Babak otoukesh to the following phone and email address be referred babak.otoukesh@gmail.com +989126843678 How to obtain: After reviewing the request will be answered within a maximum of 1 month Comments: The result of this research paper has been published and accessible to the public via the link below : https://www.termedia.pl/Evaluation-of-inflammatory-response-in-patients-undergoing-surgical-treatment-for-early-and-delayed-femoral-fractures,19,28559,1,1.html