IRCT2015121419919N7 IRCT 2016-02-01 Deputy of Research, Tabriz University of Medical Sciences The effect of oral care and honey mouthwash on the mucositis The effect of oral care program and honey mouthwash on mucositis, weight loss and quality of life of patients with Acute Myeloid leukemia undergoing chemotherapy: A Randomaized Clinical Trial 2015-12-31 anticipated 51 Complete https://irct.ir/trial/17694 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A mucositis. Intervention 1: In oral care intervention program involves the use of a soft toothbrush twice a day, flossing once, three times a day before and after every meal and before bed-time of normal saline (60 mL for 30 seconds ) will be used. Finally, a written training program will be given to the patient and his family Water will be used to protect the lips. Intervention 2: The intervention group that receive honey mouthwash, a solution of a big tablespoon of honey that will be solved in mild water gurgled and keep in the mouth that can involve the entire surface of the mouth, gums and tongue. this solution, will be three times a day, before and after eating meal and once before sleeping,for 30 seconds. Intervention 3: In the control group patients only receive routine care and intervention will be done.