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IRCT2016062720282N2 IRCT 2017-03-28 Mashhad University of Medical Sciences The Effect of Acupuncture on hemodialysis pruritus The effect of Acupuncture ,as a complementary medicine,in controlling pruritus in hemodialysis patients 2017-03-30 anticipated 30 Complete https://irct.ir/trial/18018 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 3 Renal failure under Hemodialysis. Intervention 1: Control Group: Based on inclusion and exclusion criteria,patients are selected.They fill consent and questionnaires forms then dermatologist does skin punch biopsy in the dorsal surface of the hand and prescribes Gabapentin(200-300 mg daily ) for Every patient and refers them to acupuncture clinic . Patients are located randomly in one of the 2 groups by acupuncturist through the draw of the parcel.Control group receive acupuncture by needling at 1 centimeter outside certain acupuncture point similar to intervention group, by expert, 2 times a week, for 6 weeks. After the last session of acupuncture, patients fill questionnaires again and are referred to dermatology clinic.Biopsy on the same condition is prepared and sent to pathology lab to compare the mast cell infiltration with first biopsy. Intervention 2: Intervention group: Based on inclusion and exclusion criteria,patients are selected.They fill consent and questionnaires forms then dermatologist does skin punch biopsy in the dorsal surface of the hand and prescribes Gabapentin(200-300 mg daily ) for Every patient and refers them to acupuncture clinic . Patients are located randomly in one of the 2 groups by acupuncturist through the draw of the parcel. Intervention group receive acupuncture treatment by needling in the SP10, ST36, LI4, LV3, SP6 by experts 2 times a week, for 6 weeks .After the last session of acupuncture, patients fill questionnaires again and are referred to dermatology clinic.Biopsy on the same condition is prepared and sent to pathology lab to compare the mast cell infiltration with first biopsy.
public Shapour Badiee Aval
School of Persian and Complementary Medicine
Mashhad Iran (Islamic Republic of) +98 51 3768 8519 Badieeash@mums.ac.ir Mashhad University of Medical Sciences scientific ShapourBadiee Aval
School of Persian and Complementary Medicine
Mashhad Iran (Islamic Republic of) +98 51 3768 8519 Badieeash@mums.ac.ir Mashhad University of Medical Sciences Iran (Islamic Republic of) Main Inclusion criteria are:hemodialysis patients; older than 18 years and less than 65 years old; Itching for more than 3 months despite recieving conventional therapy ;VAS scale score greater than 4;Under Hemodialysis at least 6 months ;Be able to answer the questions. Main Exclusion criteria are: Age less than 65 years or more than 18 years; history of bleeding or coagulation disorders;any history of skin disease,psychiatric disease,cancer,liver disease.;.No willing to continue acupuncture treatment during study 18 years 65 years Both N18.5 Chronic kidney disease, stage 5 Treatment - Other Treatment - Other Control Group: Based on inclusion and exclusion criteria,patients are selected.They fill consent and questionnaires forms then dermatologist does skin punch biopsy in the dorsal surface of the hand and prescribes Gabapentin(200-300 mg daily ) for Every patient and refers them to acupuncture clinic . Patients are located randomly in one of the 2 groups by acupuncturist through the draw of the parcel.Control group receive acupuncture by needling at 1 centimeter outside certain acupuncture point similar to intervention group, by expert, 2 times a week, for 6 weeks. After the last session of acupuncture, patients fill questionnaires again and are referred to dermatology clinic.Biopsy on the same condition is prepared and sent to pathology lab to compare the mast cell infiltration with first biopsy. Intervention group: Based on inclusion and exclusion criteria,patients are selected.They fill consent and questionnaires forms then dermatologist does skin punch biopsy in the dorsal surface of the hand and prescribes Gabapentin(200-300 mg daily ) for Every patient and refers them to acupuncture clinic . Patients are located randomly in one of the 2 groups by acupuncturist through the draw of the parcel. Intervention group receive acupuncture treatment by needling in the SP10, ST36, LI4, LV3, SP6 by experts 2 times a week, for 6 weeks .After the last session of acupuncture, patients fill questionnaires again and are referred to dermatology clinic.Biopsy on the same condition is prepared and sent to pathology lab to compare the mast cell infiltration with first biopsy. Pruritus. Timepoint: before and after intervention. Method of measurement: VAS questionnaire. Mast cell infiltration. Timepoint: Before and after intervention. Method of measurement: The number of mast cells per microscopic magnification 40 after Giemsa stain. Quality of life. Timepoint: Before and after. Method of measurement: Quality life questionnaire. Mashhad University of Medical Sciences Approved 2015-07-22 Mashhad University of Medical Sciences Daneshgah 16 Mashhad Iran (Islamic Republic of)